Using of oral midodrine in weaning of vasoactive infusions in patients admitted with septic shock / (Record no. 74812)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03378cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032426.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 191027s2019 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.09.M.Sc.2019.Ab.U |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Abdulahad Mohammed Ali |
| 245 10 - TITLE STATEMENT | |
| Title | Using of oral midodrine in weaning of vasoactive infusions in patients admitted with septic shock / |
| Statement of responsibility, etc. | Abdulahad Mohammed Ali ; Supervised Ahmed Hussien Alsherif , Karim Salem Mashhoor , Mohammed Amin Fakher |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | إستخدام عقار الميدودرين فى فطام الأدوية القابضة للأوعية الدموية فى مرضى الصدمة الإنتانية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Abdulahad Mohammed Ali , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 131 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Critical Care Medicine |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Patients admitted to intensive care units (ICU) are often treated with intravenous (IV) vasopressors. Persistent hypotension and dependence on IV vasopressors in otherwise resuscitated patients lead to delay in discharge from ICU. Midodrine is an oral alpha-1 adrenergic agonist approved for treatment of symptomatic orthostatic hypotension. The use of midodrine as a vasopressor sparing agent has steadily increased in the ICU despite limited evidence for this off label use. Objectives: To evaluate the role of midodrine in weaning of vasopressor infusions in patient admitted to ICU with septic shock, and to evaluate of the effect of midodrine on outcome of septic patients regarding length of ICU stay and ICU mortality. Patients and Methods: This study was a randomized controlled intervention trial, being conducted in the critical care department, Kasr Elainy hospital, Cairo university, Cairo, Egypt. We targeted 60 patients. Adult patients aged {u2265}18 years, admitted to the ICU with diagnosis of septic shock and who were on IV vasopressors for at least 24 h were considered for recruitment. Participants were randomized to either receive midodrine, 10 mg three times a day, or not in addition to standard care. The primary outcome is the time (hours) from initiation to discontinuation of IV vasopressors and duration of weaning. Secondary outcomes include ICU LOS (days), ICU mortality rate. Results: The IV vasopressor duration (hours) and IV vasopressor weaning duration (hours) were lower in the midodrine group when compared to IV vasopressor only group but the difference is statistically insignificant (139.03±46.95 VS 141.90±79.77 and 62.37±14.94 VS 74.20±36.78 respectively). MAP was significantly improved in midodrine group from 84.50 mmHg at the time of midodrine initiation to 88.03 mmHg after 24hours of midodrine initiation (p=0.04) No differences in secondary outcomes, including ICU length of stay and ICU mortality, were observed |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hypotension |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Intensive care unit |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Septic shock |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Hussien Alsherif , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Karim Salem Mashhoor , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohammed Amin Fakher , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.09.M.Sc.2019.Ab.U | 01010110079598000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.09.M.Sc.2019.Ab.U | 01020110079598000 | 22.09.2023 | CD - Rom | 79598.CD |