Animal model of febrile seizures and epileptogenesis / (Record no. 76204)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02735cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032510.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200104s2019 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.04.M.Sc.2019.He.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Heba Mohamed Sayed Ibrahim |
| 245 10 - TITLE STATEMENT | |
| Title | Animal model of febrile seizures and epileptogenesis / |
| Statement of responsibility, etc. | Heba Mohamed Sayed Ibrahim ; Supervised Maha Anwar Ali , Haitham Sharaf Eldin Mohammed , Heba Salah Eldin |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | نموذج حيوانى للنوبة الحموية وتكون الصرع |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Heba Mohamed Sayed Ibrahim , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 78 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biophysics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Febrile seizures (FS) are convulsions accompanied with elevation in body temperature. It{u2019}s highly prevalent in children between 6 months to 5 years old and may have detrimental effects in adulthood. In the present study, an experimental animal model of FS was designed by exposing young animals to hyperthermia. Oxidative stress parameters (malondialdehyde, nitric oxide, reduced glutathione) and acetylcholinesterase activity were analyzed in the hippocampus and cortex of immature hyperthermic and adult animals exposed to hyperthermia while immature and control animals.The electroencephalogram (EEG) was also recorded in adult hyperthermia-exposed rats. Moreover, behavioral assessment of seizure threshold and its severity was obtained by injection of a sub- convulsive dose of nicotine to adult animals. Alterations in the oxidant / antioxidant system and AchE activity occurred in the hippocampus and cortex of FS animals relative to control ones. Significant changes in all EEG frequency bands were obtained by spectral analysis of EEG of adult hyperthermia-exposed animals. Seizure susceptibility observation and scaling revealed a decrease in seizure threshold and increase in seizure severity. The present study emphasizes the correlation between prolonged FS encountered at immature age and long lasting brain abnormalities at adulthood which may be related to the underlying mechanism of epileptogenesis and its related co{u2013}morbid |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Febrile seizures (FS) |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hyperthermia |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Oxidative stress |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Haitham Sharaf Eldin Mohammed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Heba Salah Eldin , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maha Anwar Ali , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.04.M.Sc.2019.He.A | 01010110080550000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.04.M.Sc.2019.He.A | 01020110080550000 | 22.09.2023 | CD - Rom | 80550.CD |