Treatment of anemia using nanoparticles / (Record no. 76496)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02851cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032519.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200203s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.04.M.Sc.2020.As.T |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Asmaa Mohammed Mohammed Balah |
| 245 10 - TITLE STATEMENT | |
| Title | Treatment of anemia using nanoparticles / |
| Statement of responsibility, etc. | Asmaa Mohammed Mohammed Balah ; Supervised Wael M. Elshemey , Heba Mohamed Fahmy , Mohamed Mahmoud Fathy |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | علاج الأنيميا باستخدام الجسيمات النانو مترية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Asmaa Mohammed Mohammed Balah , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 110 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biophysics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Iron deficiency anemia (IDA) is a major worldwide public health problem. This is due to its prevalence among infants, children, adolescents, pregnant and reproductive age women. Ferrous sulfate (FeSO4) is the first line therapy for iron IDA. Unfortunately, it is reported that FeSO₄ suffers from low absorption rate in the body and itself exhibits severe side effects. Herein, iron oxide magnetic nanoparticles-loaded liposomes (LMNPs) are prepared, characterized and evaluated as a treatment regimen for IDA in Wistar rats (as an animal model). Iron oxide magnetic nanoparticles (MNPs) are prepared and loaded into liposomes using the thin film hydration method. The physiochemical properties of the prepared nano-formulations are characterized using several techniques. Transmission electron microscopy (TEM) revealed that MNPs are synthesized (with a size of about 7 nm) and successfully loaded into liposomal carrier. Dynamic light scattering (DLS) reveals that the hydrodynamic size of prepared LMNPs is about 125 nm. Thus it can avoid the reticular endothelial system (RES), give better distribution throughout the tissues, besides offering an increased blood circulation time. For in vivo assessment, thirty-five Wistar rats are divided into 5 groups (n=7): negative control group, positive control group and three groups treated with different iron formulations (FeSO4, MNPs and LMNPs). Anemia is induced in the anemic groups by the bleeding method and then treatment started with X different iron compounds administrated orally for 13 days. Hematological parameters are followed up during the treatment period |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Iron deficiency anemia |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Liposome |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Magnetic nanoparticles |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Heba Mohamed Fahmy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wael M. Elshemey , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.04.M.Sc.2020.As.T | 01010110080711000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.04.M.Sc.2020.As.T | 01020110080711000 | 22.09.2023 | CD - Rom | 80711.CD |