Topical tranexamic acid versus topical vitamin c with microneedling in periorbital hhyperpigmentation : (Record no. 77389)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03654cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032547.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200825s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.10.M.Sc.2020.Do.T |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Doaa Mohsen Fadl Morsy |
| 245 10 - TITLE STATEMENT | |
| Title | Topical tranexamic acid versus topical vitamin c with microneedling in periorbital hhyperpigmentation : |
| Remainder of title | Comparative study / |
| Statement of responsibility, etc. | Doaa Mohsen Fadl Morsy ; Supervised Nahla Shoukry Hunter , Marwa Ahmed Amer |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة مقارنة لعلاج الهالات السوداء حول العينين باستخدام حمض الترانيكساميك الموضعى مقابل فيتامين ج الموضعى مع الوخز بالابر الدقيقة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Doaa Mohsen Fadl Morsy , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 127 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background:Periorbital hyperpigmentation (POH) is a commonly encountered condition that affects both genders with female predominance. It presents as bilateral circular or semicircular homogenous light or dark brown pigmentation in the periorbital region. Various exogenous and endogenous factors are implicated in its pathogenesis and treatment is considered to be challenging. Vitamin C, an essential dietary nutrient, plays a role in the maintenance of proper skin functions through its action on wound healing, photoprotection, skin hydration, antiaging, as well as depigmentation. Tranexamic acid (TXA) has lately gained popularity as an adjuvant therapy in some pigmentary disorders especially melasma.Aim of work: The present study aims at evaluating and comparing the therapeutic effect of topical tranexamic acid solution in POH compared to topical vitamin C solution, both combined with microneedling. Patients and methods:Fifty eight patients, twenty nineeach group,were subjected to detailed medical history, clinical examination of the skin, digital photography and dermoscopic evaluation at weeks 0, 10. One eye was treated with 20% topical vitamin C solution in group A and with topical TXA 5mg/ ml solution in group B. The other eye was treated with 0.9% NaCl as a placebo in both groups both combined with microneedling.A session was done every two weeks over a period of six weeks with a total of four treatments. Patients came one month after the last session for evaluation. Dermatology life quality index (DLQI) and visual analogue score (VAS) were performed by the patients giving a score from 0 to 30 for DLQI and0 to 10 for VAS, at weeks 0 and 10. At week 10,percentage of dermoscopic improvement was evaluated using a score from 0 to 4, also two blinded physicians evaluated percentage of clinical improvement using a score from 0 to 4 and their results were averaged.Results:In both groups, group A (treated with Vit.C) and group B (treated with TXA) clinical grading at week 10showed significant improvement compared to week 0, there wasstatistically significant improvement of POH by dermoscopy in the eye treated with Vit. C or TXA compared to eye treated with saline (placebo) |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Periorbital hyperpigmentation |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Tranexamic acid |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Vitamin C |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marwa Ahmed Amer , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nahla Shoukry Hunter , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.10.M.Sc.2020.Do.T | 01010110081334000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.10.M.Sc.2020.Do.T | 01020110081334000 | 22.09.2023 | CD - Rom | 81334.CD |