The impact of some pesticides on gene expressions in male albino rats / (Record no. 78104)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03313cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032609.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201006s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.02.M.Sc.2020.Sh.I |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Shimaa Mohamed Abdelrahman |
| 245 14 - TITLE STATEMENT | |
| Title | The impact of some pesticides on gene expressions in male albino rats / |
| Statement of responsibility, etc. | Shimaa Mohamed Abdelrahman ; Supervised Eman A. Ragab , Heba.M. Kamal , Khairy Abdelmoneim Ibrahim |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثير بعض المبيدات على التعبيرات الجينية فى ذكور الجرذان البيضاء |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Shimaa Mohamed Abdelrahman , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 155 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Exposure to a pesticide is a very important subject that must keep in our mind as they may possess some neurotoxic properties to animals and human specifically and may cause neuro degenerative diseases, so in our study we shall to study the possible adverse effects of individual and combination of cypermethrin, a pyrethroid and chlorpyrifos, an organophosphate on adult male albino rats. Cypermethrin (25.089 mg/kg) and chlorpyrifos (16.324 mg/kg.) in addition their mixture at low doses were orally administrated to (12-14 week old) male albino rats (six animals per each one) for consecutive twenty eight days. At the end of the experiment, brain was frozen and saved until being used for (AChE and MAO) brain genes expression ,histopathological examination of some brain regions beside some liver enzymes (AST &ALT) and kidney functions (urea and creatinine) and lipid profile for our tested animals. It was found that brain acetyl cholinesterase, monoamine oxidase were significantly decreased after individually and combined intoxication with two tested pesticides. The same result was recorded in body weight after individual intoxications with cypermethrin and chlorpyrifos and LDL-C after toxicity with the mixture while creatinine was insignificantly decreased after toxicity with Cypermethrin beside the mixture, urea after toxicity with chlorpyrifos and cholesterol after toxicity with all type of our tested pesticides .on the other hand increasing in AST, ALT, Triglycerides and HDL-C after intoxication of individual pesticides and their mixture were observed while urea was insignificant increased after toxicity with cypermethrin beside the mixture. From our data we can find that cypermethrin and/or chlorpyrifos caused disruption in liver & kidney functions and lipid metabolism .also it caused reduction in neurotransmitters and their metabolizing enzymes. We suggested that these impacts supposed to affect the brain development and function of our tested animals in adult stage |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Chlorpyrifos |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cypermethrin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Mixture |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Eman A. Ragab , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Heba.M. Kamal , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Khairy Abdelmoneim Ibrahim , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.02.M.Sc.2020.Sh.I | 01010110081698000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.02.M.Sc.2020.Sh.I | 01020110081698000 | 22.09.2023 | CD - Rom | 81698.CD |