Evaluation of the protective potentials of clostridium perfringens NetB toxin-based vaccine in broiler chickens / (Record no. 78739)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 03129cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032628.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201114s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.10.10.Ph.D.2020.Am.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Amal Nader Awad Elrasheed |
| 245 10 - TITLE STATEMENT | |
| Title | Evaluation of the protective potentials of clostridium perfringens NetB toxin-based vaccine in broiler chickens / |
| Statement of responsibility, etc. | Amal Nader Awad Elrasheed ; Supervised Heidy Mohamed Shawky , Mahmoud Elhariri , Eman Fathy Farag |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم امكانات الحماية للقاح القائم على كلوستريديم برفرنجينز نت بى فى دجاج التسمين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Amal Nader Awad Elrasheed , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 115 P. : |
| Other physical details | charts , facimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Microbiology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | A total of 200 samples representing intestinal content of apparently healthy and diseased broiler chickens showing enteric disorder symptoms and lesions suspected to be due to necrotic enteritis, were examined by conventional and molecular methods. C.perfringens was isolated with an incidence of 10% (10/100) from apparently healthy chickens, and with an incidence of 25% (25/100) from diseased chickens.Twenty isolates of C.perfringens were proved to be toxigenic with an incidence of 57.1% (20/35), while 42.8% (15/35) were non-toxigenic. Multiplex PCR was performed to toxinotype the 35 C.perfringens isolates, the result showed that all isolates were positive for the alpha toxin gene. Experimental infection with multiple doses of Clostridium perfringens toxoidtype A, C, Net B given S/C in chicken resulted in subclinical necrotic enteritis (NE) diagnosed by decreased body weight gain and. histopathological lesions in intestine and liver. Intestinal samples were collected at 3,7,14 and 37 days after vaccination for enumerating Clostridium perfringens in all groups. Vaccinated groups showed a decreas in Clostridium perfringens count compared with negative and positive groups. Immune response to vaccination by toxoid of type A, type C and type A Net B positive, was estimated. The effect of toxoid administration on intestinal secretory immunoglobuline revealed significant increase in SIgA in all vaccinated groups. Moreover, detection of interleukin 4 also gave a high level in group (2) vaccinated with toxoid A+ NetB while Net B positive type C group (3) showed a steady regulated level. Regarding interleukin 10, regulation has been shown in all immunized groups compared with control {u2013}ve group |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Beta like toxin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | C.perfringens |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Necrotic enteritis (NE) |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Eman Fathy Farag , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Heidy Mohamed Shawky , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mahmoud Elhariri , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.10.10.Ph.D.2020.Am.E | 01010110082013000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.10.10.Ph.D.2020.Am.E | 01020110082013000 | 22.09.2023 | CD - Rom | 82013.CD |