Study of the level of tumor necrosis factor like weak inducer of apoptosis (TWEAK) in psoriasis, atopic dermatitis and healthy controls : (Record no. 78988)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03036cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032637.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201128s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.10.M.Sc.2020.As.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Asmaa Mahmoud Mohamed |
| 245 10 - TITLE STATEMENT | |
| Title | Study of the level of tumor necrosis factor like weak inducer of apoptosis (TWEAK) in psoriasis, atopic dermatitis and healthy controls : |
| Remainder of title | A comparative study / |
| Statement of responsibility, etc. | Asmaa Mahmoud Mohamed ; Supervised Hanan Rabea Nada , Heba Ahmed Abdelkader , Laila Ahmed Rashed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة مستوى عامل نخر الورم محفز للإستماتة (تويك) فى مرض الصدفية والتهاب الجلد التأتبى ومقارنته فى الضابط : |
| Remainder of title | دراسة مقارنة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Asmaa Mahmoud Mohamed , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 107 P. : |
| Other physical details | charts , facimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Psoriasis and atopic dermatitis (AD) are common, chronic, inflammatory, T-cell-mediated diseases. Both are multifactorial diseases with skin-barrier disruption, genetic, environmental and immunological factors contributing to their pathogenesis. Tumor necrosis factor- (TNF-) like weak inducer of apoptosis (TWEAK) is a member of the TNF ligand superfamily. Previous studies suggested a role of TWEAK/Fn14 pathway in psoriasis and atopic dermatitis. However, studies are quite limited with some controversial results. Objective: To further elucidate the role of TWEAK in psoriasis and AD and to explore its relation with clinical variables of both diseases. Methods: A case control study was conducted on 90 subjects; 30 patients with psoriasis, 30 patients with atopic dermatitis and 30 age and sex matched healthy controls. Skin biopsies were obtained from the lesional skin of patients and normal skin of controls to determine the level of tissue TWEAK (pg/mg) by ELISA. Results: TWEAK level was significantly higher in patients with psoriasis or atopic dermatitis compared to controls. A statistically significant difference was found between the level of TWEAK in patients with psoriasis and those with AD, being higher in patients with psoriasis. TWEAK level showed a significant positive correlation with AD disease duration. Limitations: Limitations of this study are the exclusion of clinical types of psoriasis and AD, other than vulgaris type and adult AD, respectively and exclusion of paediatric patients |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Atopic dermatitis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Psoriasis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | TWEAK |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hanan Rabea Nada , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Heba Ahmed Abdelkader , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Laila Ahmed Rashed , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.10.M.Sc.2020.As.S | 01010110082185000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.10.M.Sc.2020.As.S | 01020110082185000 | 22.09.2023 | CD - Rom | 82185.CD |