Synthesis and biological evaluation of novel bis(heterocyclic compounds) / (Record no. 79233)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02772cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032644.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201217s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.10.Ph.D.2020.El.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Elshimaa Mohmed Elsaied Eid |
| 245 10 - TITLE STATEMENT | |
| Title | Synthesis and biological evaluation of novel bis(heterocyclic compounds) / |
| Statement of responsibility, etc. | Elshimaa Mohmed Elsaied Eid ; Supervised Ahmed Helmy Elwahy , Huwaida M. E. Hassaneen , Ismail A. Abdelhamid |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | التشييد والتقييم البيولوجي لمركبات غير متجانسة الحلقة الثنائية و المتماثلة الجديدة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Elshimaa Mohmed Elsaied Eid , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 165 P . : |
| Other physical details | charts , facsmilies ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Organic Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Part I: Facile one-pot, three-component synthesis of novel series of bis(2-amino-3- cyano-4H-chromene), bis((2-amino-3-cyanopyrano[3,2-c]chromene, 6-amino-5-cyano- 1,4-dihydropyrano[2,3-c]pyrazole and bis(2,7-diamino-3,4,6-tricyanopyrazolo[1,5- a]pyridine) derivatives linked to thieno[2,3-b]thiophene-2,5-dicarboxylate core via ether as well as ester linkages were performed via Michael addition reaction. Part II: A novel series of bis(hexahydroacridine-1,8-diones), bis(tetrahydrodipyrazolo[3,4-b:4',3'-e]pyridines) and bis(pyrimido[4,5-b]quinolines) incorporating thieno[2,3-b]thiophenes core via ether as well as ester linkages were prepared via Hantzsch like reaction. All the compounds showed varying degree of Ü- glucosidase inhibition, compound 7c showed promising inhibitory activity. Part III: A synthesis of novel bis(thiazoles) as well as bis(thiadiazoles) each linked to thienothiophene moiety from the corresponding bis(aldehyde thiosemicarbazones) is reported. The bis(aldehyde thiosemicarbazones) were obtained by condensation of the appropriate bis(aldehydes) with thiosemicarbazide. Part IV: Novel bis(tetrahydro-[1,2,4]triazolo[3,4-a]isoquinolin-3-yl)-3-arylprop-2-en-1- one) derivatives were synthesized The novel compounds were screened for their cytotoxicity against cancer cell lines. Also, the compounds were screened for their antibacterial activities |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Bis(aldehydes) |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hantzsch like reaction |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Michael addition |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Helmy Elwahy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Huwaida M. E. Hassaneen , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ismail A. Abdelhamid , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.10.Ph.D.2020.El.S | 01010110082345000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.10.Ph.D.2020.El.S | 01020110082345000 | 22.09.2023 | CD - Rom | 82345.CD |