Genotoxicity and cytotoxicity of gold Nanoparticles / (Record no. 79353)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02558cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032648.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201227s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.04.M.Sc.2020.Fa.G |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Fatma Alzahraa Sayed Mohammed |
| 245 10 - TITLE STATEMENT | |
| Title | Genotoxicity and cytotoxicity of gold Nanoparticles / |
| Statement of responsibility, etc. | Fatma Alzahraa Sayed Mohammed ; Supervised Ahmed Soltan Abdelmonem , Monira Mahmoud Rageh , Noha Mohammed Sayed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | السمية الوراثية والسمية الخلوية لجزيئات الذهب النانومترية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Fatma Alzahraa Sayed Mohammed , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 83 P . : |
| Other physical details | charts , facsmilies ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biophysics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The aim of this work is to evaluate the cytotoxicity and genotoxicity of pegylated gold nanorods (PEG/GNRs) as photothermal agents. The treatment protocol using PEG/GNRs was compared with that protocol using cisplatin as a regular chemotherapeutic drug. The former formulation found to have a high efficacy in treating tumors induced in experimental animals. The formulation was characterized by measuring its absorption spectra, zeta potential and transmission electron microscope. The cytotoxicity and genotoxicity of mice liver, kidney and tumor tissues were determined by measurement of malondialdehyde (MDA) levels, super oxide dismutase (SOD) activity, DNA damage and observing its histopathological changes.The results showed that the treated mice exhibited decreased levels of SOD in tumor tissues. The induced oxidative stress due to tumor growth in liver and kidney tissues showed a marked decrease indicated by the increase in SOD. The former results were also confirmed by measuring MDA, comet parameters and the histopathological examination. The formulation prepared in this work showed a high efficacy in treating Ehrlich tumor marked by diminishing its volume and so reducing its related oxidative stress on the critical organs |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cytotoxicity |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Genotoxicity |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Gold nanorods |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Soltan Abdelmonem , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Monira Mahmoud Rageh , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Noha Mohammed Sayed , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.04.M.Sc.2020.Fa.G | 01010110082393000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.04.M.Sc.2020.Fa.G | 01020110082393000 | 22.09.2023 | CD - Rom | 82393.CD |