Ameliorative effect of coelatura aegyptiaca extract on hyperlipidemia induced multiple organs injury in rats / (Record no. 79434)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03484cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032650.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210103s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.21.M.Sc.2020.Wa.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Walaa Muhammad Ibrahim Mahmoud |
| 245 10 - TITLE STATEMENT | |
| Title | Ameliorative effect of coelatura aegyptiaca extract on hyperlipidemia induced multiple organs injury in rats / |
| Statement of responsibility, etc. | Walaa Muhammad Ibrahim Mahmoud ; Supervised Amel Mahmoud Soliman , Nashwah Ismail Zaki , Ayman Saber Mohamed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | التأثير المحسن لمستخلص السيلاتيورا إجيبتياكا على اصابة العديد من الأعضاء المستحث بارتفاع مستوى الدهون فى دم الجرذان |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Walaa Muhammad Ibrahim Mahmoud , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 181 P . : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science- Department of Zoology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | High-fat diet (HFD) feeding can induce obesity in rats that resemble human metabolic syndrome. Obesity is one of the most prevalent health conditions which may be associated with various diseases such as dyslipidemia, hypertension, and increased risks of cardiovascular diseases. Egyptian freshwater clam Coelatura aegyptiaca is a Molluscan bivalve belonging to Unionoidae common in the Egyptian River Nile. Consumption of these clams as food by humans may significantly influence their health status. The present study aimed to investigate the anti-hyperlipidemic mechanisms of the clam extract (CE) in the rat model of high fat diet-induced hyperlipidemia. Furthermore, the aim of this study extends to investigate the efficacy of CE to ameliorate the side effects of the standard drug atorvastatin (antihyperlipidemic drug). Forty male Wistar rats were divided into five groups (8 rats/group); control, high-fat diet (HFD), atorvastatin (ATOR), Coelatura aegyptiaca extract (CE), and ATOR + CE. A high-fat diet (HFD) was induced hyperlipidemia with the energy of 5.3 kcal/g, comprising 60% calories from fat, 35% from protein, and 5% from carbohydrate for 4 weeks. CE group showed a reduction in the body weight gain, the concentrations of triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), urea, uric acid, malondialdehyde (MDA), serum activity of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), creatinine and creatine kinase (CK). While, it caused a general increase in the levels of total protein (TP), albumin, high-density lipoprotein cholesterol (HDL- C), as soon as the activities of glutathione-S-transferase (GST), glutathione reduced (GSH) and catalase (CAT). The histopathological investigation showed improvement in the hepatic, kidney, and muscle tissues. The results of this study clearly show that CE has anti-hyperlipidemic potential through its antioxidant activity against high-fat diet-induced hyperlipidemia |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Coelatura aegyptiaca |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hyperlipidemia |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Oxidative stress |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Amel Mahmoud Soliman , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ayman Saber Mohamed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nashwah Ismail Zaki , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.21.M.Sc.2020.Wa.A | 01010110082462000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.21.M.Sc.2020.Wa.A | 01020110082462000 | 22.09.2023 | CD - Rom | 82462.CD |