Assessment of the level of serum and tissue Coenzyme q10 in Pemphigus Vulgaris patients versus controls : (Record no. 79510)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02849cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032653.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210110s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.10.M.Sc.2020.Em.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Eman Assaad Hamed Ibrahim |
| 245 10 - TITLE STATEMENT | |
| Title | Assessment of the level of serum and tissue Coenzyme q10 in Pemphigus Vulgaris patients versus controls : |
| Remainder of title | A case control study / |
| Statement of responsibility, etc. | Eman Assaad Hamed Ibrahim ; Supervised Marwah Adly Mohamed Saleh , Heba Ahmed Mohamed Ahmed Abdelkader , Laila Ahmed Rashed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة الحالات والشواهد : |
| Remainder of title | تقييم مستوى الإنزيم المساعد كيو 10 فى مصل الدم والأنسجة فى مرضى ذو الفقاع الشائع مقارنة بالأصحاء |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Eman Assaad Hamed Ibrahim , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 96 P. : |
| Other physical details | charts , facsmilies ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine- Department of Dermatology and Venerology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Pemphigus vulgaris (PV) is a life-threatening autoimmune blistering disease of the skin and mucous membranes. It occurs due to the action of autoantibodies against various keratinocyte self-antigens. Antimitochondrial autoantibodies were detected in PV. Coenzyme Q10 (CoQ10) is a member of the mitochondrial respiratory chain that is involved in cellular metabolism including apoptosis. Objective: to assess the level of CoQ10, both in serum and tissue, in PV patients versus healthy controls to determine its relevance to the pathogenesis of the disease. Methods: A case control study included twenty patients with pemphigus vulgaris and twenty age- and sex-matched controls. Blood and skin samples were collected for the measurement of CoQ10 level by ELISA. Results: CoQ10 was significantly lower both in serum and tissue of PV patients compared to controls (p=0.001). Similar results were found when gender subgroups were compared separately. A significant positive correlation was found between serum and tissue CoQ10 levels in controls but not in PV patients (p=0.019, r=0.521). Conclusion: CoQ10 appears to be one of the victims of the autoimmune response in PV, adding to the tissue damage caused by autoantibodies. CoQ10 supplementation might be of value in the treatment of PV |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Desmoglein1 |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | human leucocyte antigen |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Pemphigus vulgaris |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Heba Ahmed Mohamed Ahmed Abdelkader, |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Laila Ahmed Rashed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marwah Adly Mohamed Saleh , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.10.M.Sc.2020.Em.A | 01010110082476000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.10.M.Sc.2020.Em.A | 01020110082476000 | 22.09.2023 | CD - Rom | 82476.CD |