Studies on endophytic fungi associated with Thymus vulgaris and their biological activities / (Record no. 80729)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03344cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032730.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210424s2021 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.05.M.Sc.2021.Ma.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Marwa Ragab Hamed |
| 245 10 - TITLE STATEMENT | |
| Title | Studies on endophytic fungi associated with Thymus vulgaris and their biological activities / |
| Statement of responsibility, etc. | Marwa Ragab Hamed ; Supervised Mohsen Abuelela Sayed , Eman Abdullah Mohamed , Ahmed Abdelaziz Ahmed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراساث على الفطرياث الداخلية المصاحبة لنبات الزعتر والأنشطة الحيوية لها |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Marwa Ragab Hamed , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 116 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Botany - Microbiology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The present study aimed to study the endophytic mycoflora of Thymus vulgaris L. which is an important aromatic and medicinal plant and assaying the antimicrobial, anticancer, total phenolic content and antioxidant activities for the different plant and fungal extracts against some pathogens with elucidation of the active components using GCMS, FTIR and HPLC. A total four morphological distinct endophytic fungi were isolated and identified. From the extracellular and cultivation mats, bioactive metabolites has been extracted using ethyl acetate to prepare the endophytic extracts, the different plant extract were prepared using ethyl acetate in one of them and methanol in the other. Antimicrobial property was assessed through disc diffusion method and DPPH assay was performed to measure the free radical scavenging activity of the extracts, on the other hand the cytotoxic potential of the fungal and plant extracts against hepatocellular carcinoma cell line (HepG2)was studied by CVS assay. The active compounds present in the extracts were identified by GC.MS, FTIR and HPLC analysis.The dominant fungal extract (A. terreus extract) showed a strong growth inhibtory effect against bacterial human pathogen and excellent free radical scavenging activity with the highest content of phenolic. It also exhibits excellent effect against hepatocellular carcinoma cells the active compounds present in the extract were identified which depicts the presence of phenolic especially carvacrol in a large amount comparing with other extracts. Its concentrations is identified by HPLC which equal 86.25 mg/g.Overall, this study suggests that extract of isolated endophytic fungi A. terreus from Thymus vulgaris can be developed as source in view of pharmaceutical context that it contains alarge concentration of carvacrol which was actualy present in Thyme. We can say that the activity of plant against different biological processes is come from its endophytic fungi activity |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Antimicrobial |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Endophytic fungi |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Thymus vulgaris |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Abdelaziz Ahmed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Eman Abdullah Mohamed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohsen Abuelela Sayed , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.05.M.Sc.2021.Ma.S | 01010110083312000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.05.M.Sc.2021.Ma.S | 01020110083312000 | 22.09.2023 | CD - Rom | 83312.CD |