MARC details
| 000 -LEADER |
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| fixed length control field |
02977cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250223032834.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
211024s2021 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
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| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.12.05.M.Sc.2021.Da.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Dalia Omar Abdelazem Elsafty |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Antimicrobial studies of citrullus colocynthis collected from different ecological habitats in Egypt / |
| Statement of responsibility, etc. |
Dalia Omar Abdelazem Elsafty ; Supervised Mohamed Ibrahim Ahmed Ali , Salama A. Ouf , Maha G. Haggag |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
دراسة تأثير الحنظل كمضاد للميكروبات من بيئات مختلفة فى مصر |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Dalia Omar Abdelazem Elsafty , |
| Date of publication, distribution, etc. |
2021 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
124 P. : |
| Other physical details |
charts , facsimiles , maps ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Botany - Microbiology |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Aqueous and methanolic seed extracts of Citrullus colocynthis from different geographical habitats, namely Sinai, ElWadi ElGedid, and Wadi Qena, were screened for antimicrobial activities.The tested microorganisms include 18 species, of which 6 bacteria, 6 Candida, and 6 dermatophyte fungi. The methanolic extract was more effective than aqueous extract for all microorganisms.The extracts were variably effective with more significant inhibition towards dermatophytes, particularly the seeds from Sinai.The effect of methanol seed extract from Sinai combined with 0.5 og/ml fluconazole act as a synergistic factor in decreasing spore viability, reduction of keratinase, elastase, lipase, phospholipase, and protease was more pronounced. The phytochemical analyses of the methanolic seed extracts from the three localities shows the presence of Hexadecanoic acid, methyl ester, 9,12- Octadecadienoic acid (Z,Z), and 9,12-Octadecadienoic acid (Z,Z)-, 2-hydroxy-1- (hydroxymethyl) ethyl ester as common compounds.The in-silico docking activity of 9,12-Octadecadienoic acid (Z,Z), Methyl 9-cis,11-trans-octadecadienoate, and 9,12-Octadecadienoic acid, methyl ester, (E,E) toward keratinase and lipase enzymes of Microsporum canis and Trichophyton mentagrophytes showed a high affinity of binding between 9,12-Octadecadienoic acid (Z,Z) and lipase enzyme of Microsporum canis and Trichophyton mentagrophytes as it forms 3 H-bonds with Gln 106, Ser 107, and Thr 102 of Microsporum canis lipase, in addition, it forms 4 H-bonds with Gln 129, Gly 124, Ile 128, and Ser 130 of Trichophyton mentagrophytes lipase |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
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| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Antimicrobial activity |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Bacteria |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Citrullus colocynthis |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Maha G. Haggag , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohamed Ibrahim Ahmed Ali , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Salama A. Ouf , |
| Relator term |
|
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Shimaa |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |