A comparative chemical and biological investigation of selected species from the genus centaurea growing in Egypt / (Record no. 83910)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02950cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032910.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220109s2021 ua do f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.07.Ph.D.2021.Em.C |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Eman Hussein Reda Mahmoud |
| 245 14 - TITLE STATEMENT | |
| Title | A comparative chemical and biological investigation of selected species from the genus centaurea growing in Egypt / |
| Statement of responsibility, etc. | Eman Hussein Reda Mahmoud ; Supervised Elsayeda A. Elkashoury , Ali M. El Halwany , Khaled A. Shams |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | فحص كيميائى وبيولوجى مقارن لأنواع مختارة من جنس السنتاوريا الذى ينمو فى مصر |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Eman Hussein Reda Mahmoud , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 271 P . : |
| Other physical details | charts , photographes ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Centaurea genus is one of the largest genera of family Asteraceae consisting of 500-600 species. It is centered in the Mediterranean region and western Asia. Around 17 species of Centaurea are growing in Egypt. Reviewing the available literature on these species, there were no previous reports regarding C. pumilio. Few studies were found on C. eryngioides, C. alexandrina, C. calcitrapa, C. glomerata, C. scoparia, C. pallescens and C. lippii. A comparative chemical and biological study of the selected Centaurea species were carried out. Preliminary phytochemical screening was performed. The genetic diversity and genetic relationships between the 8 Centaurea species were investigated. Essential oil of selected Centaurea species was obtained by two different techniques, conventional hydrodistillation (HD) and microwave assisted extraction (MAE). Potential essential oil inhibitors of gyrase B enzyme and N-myristoyltransferase via an in silico molecular docking were screened to study the antibacterial activity. Gas chromatography-mass spectrometry analysis (GC-MS) of the essential oils obtained by both techniques was carried out. PCA (Principal component analysis) and AHC (Agglomerative hierarchical cluster) were used for categorization of essential oil samples. The in vitro antimicrobial activity for all essential oils was investigated against Staphylococcus aureus, Escherichia coli and Aspergillus niger. The biological activity of these Centaurea species was evaluated using sensitive and multidrug-resistant cancer cell lines |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | C. alexandrina |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | C. eryngioides |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Centaurea pumilio |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ali Mahmoud Elhalwany , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Elsayeda Ahmed Elkashoury , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Khaled Ahmed Shams , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.07.Ph.D.2021.Em.C | 01010110085188000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.07.Ph.D.2021.Em.C | 01020110085188000 | 22.09.2023 | CD - Rom | 85188.CD |