Evaluation of the efficacy and Safety of ketogenic diet in children with refractory epilepsy / (Record no. 84236)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03131cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032920.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220215s2021 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.28.M.Sc.2021.Sa.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sabry Mohamed Ali Ewais |
| 245 10 - TITLE STATEMENT | |
| Title | Evaluation of the efficacy and Safety of ketogenic diet in children with refractory epilepsy / |
| Statement of responsibility, etc. | Sabry Mohamed Ali Ewais ; Supervised Hanna Mohamed Aboulghar, Nour Mohamed Mohsen Elkhateeb |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم فاعلية و درجة أمان نظام الحمية الكيتونية الغذائى فى الأطفال المصابين بالصرع المستعصى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Sabry Mohamed Ali Ewais , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 119 P . : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Although many children with epilepsy will have seizures controlled with antiepileptic drugs (AEDs), a large percentage of patients are refractory to drug therapy and may consider initiating a ketogenic diet (KD). The term Ketogenic Diet Therapy (KDT) refers to any diet therapy in which dietary composition results in a state of ketosis. Objectives: In this study we assessed the ef{uFB01}cacy, safety and tolerability of the KD in children with refractory epilepsy. Outcome predictive values of various clinical factors were also assessed. Methods: This is a prospective study of 40 children with refractory epilepsy, treated with KD at the clinical nutrition clinic of Cairo University Children Hospital between October 2018 and July 2019, and had continuous follow-up at 2, 4 and 6 months. The non-fasting protocol was followed without hospital admission. The classic KD with a ratio 2:1 or 3:1 (grams of fat to combined carbohydrate and protein) was used Results: The median age for the enrolled patients was 43.5 months (range, 5{u2013}137 months). Seizure frequency was assessed at 2, 4 and 6 months after KD initiation for 19, 3 and 18 patients respectively at the time of their last follow up visit. Nineteen (47.5%) patients achieved <50% seizure reduction (including 12 (30%) patients who became seizure free). Three (7.5%) patients achieved > 50% seizure reduction. Seizures increased in 4 (10%) patients while remained unchanged in 14 (35%) patients. Favorable treatment outcome was associated with longer duration on the KD (p-value< 0.001), grams of fat intake (p-value=0.020) and generalized slow background in pre-diet EEG findings (p-value=0.026). Frequently reported adverse effects included gastrointestinal disturbance, hyperlipidemia and food refusal |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Safety |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Efficacy |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Ketogenic diet |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Seizures |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hanna Mohamed Aboulghar , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nour Mohamed Mohsen Elkhateeb , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.28.M.Sc.2021.Sa.E | 01010110085385000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.28.M.Sc.2021.Sa.E | 01020110085385000 | 22.09.2023 | CD - Rom | 85385.CD |