Evaluation of the genotoxicity and oxidative stress of acetamiprid insecticide on nile tilapia : (رقم التسجيلة. 84718)
[ عرض عادي ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 03969nam a2200421 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - أخر تعامل مع التسجيلة | |
| control field | 20260524130557.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220807s2022 ua dh frm 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloguing agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| Language code of summary or abstract | eng |
| -- | ara |
| 049 ## - Acquisition Source | |
| Acquisition Source | Deposite |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 632.9517 |
| 092 ## - LOCALLY ASSIGNED DEWEY CALL NUMBER (OCLC) | |
| Classification number | 632.9517 |
| Edition number | 21 |
| 097 ## - Degree | |
| Degree | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Local Call Number | Cai01.16.03.Ph.D.2022.He.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Authority record control number or standard number | Heba Moustafa Rasheed Hathout. |
| Preparation | preparation. |
| 245 10 - TITLE STATEMENT | |
| Title | Evaluation of the genotoxicity and oxidative stress of acetamiprid insecticide on nile tilapia : |
| Remainder of title | Oreochromis niloticus / |
| Statement of responsibility, etc. | Heba Moustafa Rasheed Hathout; Supervised Prof. Dr. Hassan. M. Sobhy |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم السمية الجينية والجهد التأكسدي للمبيد الحشري اسيتامبريد على البلطي النيلي |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 123p. : |
| Other physical details | charts, facsimiles ; |
| Dimensions | 25cm. |
| Accompanying material | CD |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rda content |
| 337 ## - MEDIA TYPE | |
| Media type term | Unmediated |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | volume |
| Source | rdacarrier |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of African Postgraduate Studies - Department of Natural Resources |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: p. 123-98. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | Acetamiprid (Aceta) is the most extensively used neonicotinoid which contaminate aquatic ecosystem from agricultural leaching. On juveniles of Oreochromis niloticus, the protective potential of ascorbic acid (Asc) against oxidative stress and genotoxicity induced by Aceta sub-lethal concentrations was investigated in this study. Fishes were divided into six groups and exposed to either; Asc (50 ppm), 10 ppm of Aceta, 20 ppm of Aceta, 10 ppm of Aceta and Asc (50 ppm), 20 ppm of Aceta and Asc (50 ppm). Unexposed animals were considered as control group. The experiment was conducted by the assessment of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) activities and their mRNA gene expression. DNA damage using comet assay in erythrocytes, hepatocytes and gill cells, in addition to mitotic index (MI), the existence of micronuclei (MN) and erythrocytic nuclear abnormalities (ENAs) were performed. The results showed that concentrations of Aceta (10 & 20 ppm) induced oxidative stress by decreasing the antioxidant enzyme activities and down-regulating gene expression of SOD, CAT and GPX compared to control group. However, LPO and NO levels were significantly elevated. Co-supplemented fish with Asc showed significant alleviations of oxidative status represented by substantial increases in the activities of SOD, CAT and GPX enzymes and diminished LPO and NO levels (P<0.05), along with a concomitant up-regulation of SOD and CAT gene expression (P < 0.05). There were genotoxic effects of Aceta exposure showed by the significant (P < 0.05) increase in DNA-damaged cells, MN, and ENA, meanwhile a decrease in MI. Supplementation with Asc reversed these effects in combined-exposure groups. Thus, results suggest that Aceta induced oxidative stress accompanied with genotoxicity. Further, Asc-combined exposure could be the effective treatment against Aceta-induced damage in O. niloticus. |
| 520 #3 - SUMMARY, ETC. | |
| Summary, etc. | أعدت هذه الدراسة لفحص القدرة الوقائية لحمض الأسكوربيك ضد الجهد التأكسدي والسمية الجينية المسببة بواسطة جرعات المبيد الحشري (إسيتامبريد على صغار أسماك البلطي النيلي. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Issues CD | Issued also as CD |
| 546 ## - LANGUAGE NOTE | |
| Text Language | Text in English and abstract in Arabic & English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Genotoxicity |
| 653 #1 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Acetamiprid Insecticide |
| -- | Nile Tilapia |
| -- | Oxidative Stress |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hassan. M. Sobhy |
| Relator term | thesis advisor. |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Islam M. El-Garawani |
| Relator term | thesis advisor. |
| 900 ## - Thesis Information | |
| Grant date | 01-01-2022 |
| Supervisory body | Hassan. M. Sobhy |
| Universities | Cairo University |
| Faculties | Faculty of African Postgraduate Studies |
| Department | Department of Natural Resources |
| 905 ## - Cataloger and Reviser Names | |
| Cataloger Name | Shimaa |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Home library | Current library | Date acquired | Inventory number | Full call number | Barcode | Date last seen | Copy number | Effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | 85656 | Cai01.16.03.Ph.D.2022.He.E | 01010110085656000 | 22.09.2023 | 22.09.2023 | Thesis | |
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | 13833091 | Cai01.16.03.Ph.D.2022.He.E | 01020110085656000 | 22.09.2023 | 85656.CD | 22.09.2023 | CD - Rom |