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Formulation and evaluation of anti - migraine bioadhesive buccal preparations / Yasmin Ahmed Salem Elfeky ; Supervised Nabaweya Abdelaziz , Nagia Nagib Afifi , Eman Ibrahim Soliman

By: Contributor(s): Material type: TextLanguage: English Publication details: Cairo : Yasmin Ahmed Salem Elfeky , 2011Description: 241P. : charts ; 25cmOther title:
  • صياغة وتقييم مسحضرات لاصقة بأغشية الفم لعلاج الصداع النصفى [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics Summary: Sumatriptan succinate is the prototype is the prototype of the triptans, a family of abortive agents that resemble serotonin (a brain chemical active in migraine) act rapidly and are effective for many patients having migraine .Sumatriptan is rapidly but incompletely absorbed when given orally and undergoes first - pass metabolism, resulting in a low absolute bioavailability of about 14 % peak plasma concentrations following oral does are achieved in about 2 hours . The elimination half - life of sumatriptan is about 2 hours
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Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.M.Sc.2011.Ya.F (Browse shelf(Opens below)) Not for loan 01010110055012000
CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.M.Sc.2011.Ya.F (Browse shelf(Opens below)) 55012.CD Not for loan 01020110055012000

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics

Sumatriptan succinate is the prototype is the prototype of the triptans, a family of abortive agents that resemble serotonin (a brain chemical active in migraine) act rapidly and are effective for many patients having migraine .Sumatriptan is rapidly but incompletely absorbed when given orally and undergoes first - pass metabolism, resulting in a low absolute bioavailability of about 14 % peak plasma concentrations following oral does are achieved in about 2 hours . The elimination half - life of sumatriptan is about 2 hours

Issued also as CD

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