Effect of P - glycoprotein blockers on the bioavailability of paclitaxel in experimental animals / Mona Mohamed Kamal ; Supervised Mohamed Taki Eldeen Khayyal , Mahmoud Mohamed Merzabani , Abdelmoneim Mahmoud Osman

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Mona Mohamed Kamal

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Language: English Publication details: Cairo : Mona Mohamed Kamal , 2006Description: 85 P. : ill ; 30cmOther title:

تاثير مثبطات البى - جليكوبروتين على النشاط الحيوى لعقار الباكليتاكسيل فى حيوانات التجارب [Added title page title]

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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology Summary: Paclitaxel (Taxol) is an antineoplastic agent used to treat many types of cancer poor oral absorption and consequently poor bioavailability The poor oral bioavailability results mainly from the activity of the P - glycoprotein (P - gp) efflux pump multi - drug Cyclosporine (an immunosuppressive drug) and verapamil (a calcium channel blocker) were used in this study as examples of P - gp efflux pump blockers

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Item type	Current library	Home library	Call number	Copy number	Status	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.08.09.M.Sc.2006.Mo.E (Browse shelf(Opens below))		Not for loan	01010110045913000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.08.09.M.Sc.2006.Mo.E (Browse shelf(Opens below))	45913.CD	Not for loan	01020110045913000

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Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology

Paclitaxel (Taxol) is an antineoplastic agent used to treat many types of cancer poor oral absorption and consequently poor bioavailability The poor oral bioavailability results mainly from the activity of the P - glycoprotein (P - gp) efflux pump multi - drug Cyclosporine (an immunosuppressive drug) and verapamil (a calcium channel blocker) were used in this study as examples of P - gp efflux pump blockers

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