Frequency of hereditary hemochromatosis (HFE) gene mutations in Egyptian beta thalassemia patients and its relation to iron overload / Mona Fayez Abdelgawad ; Supervised Azza Ahmed Aboulenein , Khalda Sayed Mohamed , Nermin Ahmed Eldosoky

By:

Mona Fayez Abdelgawad

Contributor(s):

Material type: Text

TextLanguage: English Publication details: Cairo : Mona Fayez Abdelgawad , 2014Description: 163 P. : charts , facsimiles ; 25cmOther title:

فى مرضى انيميا البحر المتوسط المصريين و علاقتها بزيادة نسبة الحديد HFE نسبه حدوث الطفرات الوراثيه فى جين [Added title page title]

Subject(s):

Online resources:

Click here to access online

Available additional physical forms:

Issued also as CD

Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology Summary: This study aimed to detect the most common HFE mutations (C282Y, H63D and S56C) in Egyptian beta - thalassemia patients and to study its relation to iron status in thalassemia patients. The study included 50 beta thalassemia major patients and 30 age and sex matched healthy persons as control group. Serum ferritin level was measured by ELISA for all beta thalassemia patients and control group. Serum iron and TIBC were measured and transferrin saturation was calculated for all patients. Detection of the three HFE gene mutations (C282Y, H63D and S65C) by RFLP analysis using PCR amplification and restriction enzyme digestion of DNA amplified products of thalassemic patients and control group using Sna B1,Bcl1 and hinf1 respectiveley

Tags from this library: No tags from this library for this title. Log in to add tags.

Average rating: 0.0 (0 votes)

Holdings
Item type	Current library	Home library	Call number	Copy number	Status	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.07.Ph.D.2014.Mo.F (Browse shelf(Opens below))		Not for loan	01010110063920000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.07.Ph.D.2014.Mo.F (Browse shelf(Opens below))	63920.CD	Not for loan	01020110063920000

Browsing المكتبة المركزبة الجديدة - جامعة القاهرة shelves Close shelf browser (Hides shelf browser)

Previous	No cover image available	No cover image available	No cover image available	No cover image available	No cover image available	No cover image available	No cover image available	Next
Previous	Cai01.11.07.Ph.D.2014.Mi.E Emerging bacterial pathogens in acute diarrhea in children less than five years in Cairo University hospitals /	Cai01.11.07.Ph.D.2014.Mi.E Emerging bacterial pathogens in acute diarrhea in children less than five years in Cairo University hospitals /	Cai01.11.07.Ph.D.2014.Mo.F Frequency of hereditary hemochromatosis (HFE) gene mutations in Egyptian beta thalassemia patients and its relation to iron overload /	Cai01.11.07.Ph.D.2014.Mo.F Frequency of hereditary hemochromatosis (HFE) gene mutations in Egyptian beta thalassemia patients and its relation to iron overload /	Cai01.11.07.Ph.D.2014.Mo.S Study of Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL) mRNA Expression in Patients with Systemic Lupus Erythematosus/	Cai01.11.07.Ph.D.2014.Mo.S Study of Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL) mRNA Expression in Patients with Systemic Lupus Erythematosus/	Cai01.11.07.Ph.D.2014.Ne.E Ex-vivo modeling of leukemic stem cell niche : Sub - classifying CD34⁺ population according to quiescence /	Next

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

This study aimed to detect the most common HFE mutations (C282Y, H63D and S56C) in Egyptian beta - thalassemia patients and to study its relation to iron status in thalassemia patients. The study included 50 beta thalassemia major patients and 30 age and sex matched healthy persons as control group. Serum ferritin level was measured by ELISA for all beta thalassemia patients and control group. Serum iron and TIBC were measured and transferrin saturation was calculated for all patients. Detection of the three HFE gene mutations (C282Y, H63D and S65C) by RFLP analysis using PCR amplification and restriction enzyme digestion of DNA amplified products of thalassemic patients and control group using Sna B1,Bcl1 and hinf1 respectiveley

Issued also as CD

There are no comments on this title.

to post a comment.

Click on an image to view it in the image viewer