Allogeniec peripheral blood stem cell transplantation in patients with severe aplastic anemia, comparing fludarabine based versus anti - thymocyte globuline based conditioning regimens : A retrospective study / Rasha Refaat Mohammad Aly ; Supervised Omar Abdelrahman Fahmy , Raafat Mohammad Abdelfattah
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TextLanguage: English Publication details: Cairo :  Rasha Refaat Mohammad Aly ,  2014Description: 177 P. :  charts ;  25cmOther title: - زراعة النخاع العظمى من متبرع باستخدام خلايا النخاع الجذعية الطرفية لمرضى فشل النخاع العظمى: مقارنة بين استخدام عقار الفلودارابين و استخدام جلوبيين مضاد الخلايا الثيموسية : دراسة استعادية [Added title page title]
 
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                        قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.18.M.Sc.2014.Ra.A (Browse shelf(Opens below)) | Not for loan | 01010110063923000 | ||
                            
                                
                                     
                                
                            
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                        مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.18.M.Sc.2014.Ra.A (Browse shelf(Opens below)) | 63923.CD | Not for loan | 01020110063923000 | 
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Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine
Allogeneic hematopoietic stem cell transplantation (Allo - HSCT) from an HLA matched sibling donor is the initial treatment of choice for newly diagnosed patients with severe aplastic anemia. Regarding the graft type, in 2007 The American society of hematology published data, indicating that BM grafts are preferred to PBPC grafts in young patients undergoing HLA - matched sibling donor transplantation for SAA. The conditioning regimen In order to improve survival in patients older than 30-40 years, the use of less cytotoxic but more immunosuppressive regimens including low - dose cyclo - phosphamide in combination with ATG, while adding fludarabine (Flu), might be an option
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