Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine

Behçet{u2019}s disease (BD) is a multisystem inflammatory disorder, BD etiology remains unknown, but epidemiologic findings suggest an autoimmune process that is triggered by an infectious or environmental agent in a genetically predisposed individual. Several viral agents including cytomegalovirus, Epstein-Barr virus, and varicella zoster virus, may also have some role. Try to assess the prevalence of CMV in Behçet{u2019}s disease, and its relation to disease activity (assessed by BDCAF). 75 Egyptian patients with Behçet{u2019}s disease as well as 75 (age and sex matched) apparently healthy Egyptians control. All our patients were subjected to Full history taking and thorough clinical examination. Disease activity of our patients was determined using the BDCAF. Laboratory investigations in the form of CBC, ESR, CRP, liver and kidney functions were done to all our patients. The level of CMV Ig M and Ig G was measured by ELISA and also CMV Ig M and Ig G indices were calculated to all our patients and controls

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