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Correlation between degree of hepatic fibrosis by liver biopsy and insulin resistance in chronic hepatitis C / Rasha Hassan Mohamed Kotb ; Supervised Emad Mohamed Almoetasm ,Yasser Bakr Mohamed

By: Contributor(s): Material type: TextLanguage: English Publication details: Cairo : Rasha Hassan Mohamed Kotb , 2014Description: 202 P. : facsimiles ; 25cmOther title:
  • دراسة للعلاقة بين نسبة التليف الكبدي بالعينه الكبديه ونسبة مقاومة الانسولين في مرضى فيرس سي [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine Summary: Insulin resistance (IR) occurs early in HCV infection and may affects liver fibrosis progression, treatment response and synergizes development of HCC. We thus studied prevalence of IR in HCV patients and correlation between IR and hepatic fibrosis. Fifty HCV, non diabetic patient were enrolled; Quantitative HCV RNA was assayed by PCR, histological assessment by liver biopsy was done and IR index assessed by using HOMA-IR, and an index value {u2265} 2.5 was designated IR and 10 normal subjects were studied as control. In this study prevalence of IR was 38% vs 62% p = 0.005, there is significant correlation between IR and hepatic fibrosis and inflammatory activity
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Item type Current library Home library Call number Copy number Status Barcode
Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.18.M.Sc.2014.Ra.C (Browse shelf(Opens below)) Not for loan 01010110064465000
CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.18.M.Sc.2014.Ra.C (Browse shelf(Opens below)) 64465.CD Not for loan 01020110064465000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine

Insulin resistance (IR) occurs early in HCV infection and may affects liver fibrosis progression, treatment response and synergizes development of HCC. We thus studied prevalence of IR in HCV patients and correlation between IR and hepatic fibrosis. Fifty HCV, non diabetic patient were enrolled; Quantitative HCV RNA was assayed by PCR, histological assessment by liver biopsy was done and IR index assessed by using HOMA-IR, and an index value {u2265} 2.5 was designated IR and 10 normal subjects were studied as control. In this study prevalence of IR was 38% vs 62% p = 0.005, there is significant correlation between IR and hepatic fibrosis and inflammatory activity

Issued also as CD

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