Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis

Is to assess the applications and possible indications for contrast enhanced digital mammography and its impact on characterization of breast lesions. 168 patients provided with an overall of 211breast lesions. Written informed consent was obtained. Contrast enhanced digital mammography CEDM was performed by using a digital mammography unit (Seno DS; GE, Buc, France) after injection of 1 - 1.5 ml/kg of contrast agent (omnipaque) in both CC and MLO views. Findings were correlated with the final pathological results. The average sensitivity was slightly higher for CEDM than for MX (88.99 % versus 88.07%). CEDM had a better diagnostic accuracy mainly due to improved specificity, and better positive and negative predictive values. Dual energy contrast enhanced digital mammography as an adjunct to mammography improves diagnostic accuracy compared to mammography alone

Issued also as CD