Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis

Diffusion-weighted magnetic resonance (MR) imaging is a technique that has traditionally been used in neuroimaging for the detection of acute ischemia and other intracranial disease. Recently, diffusion-weighted imaging (DWI) has emerged as a diagnostic technique in the evaluation of various abdominal lesions. (Chow et al., 2005). The MR signal at diffusion-weighted imaging depends on two factors: the amplitude of random displacements of water molecules (related to the ADC value) and, to a lesser extent, the b value (degree of diffusion weighting). The b value is determined on the basis of the strength and duration of the paired gradients and the time interval between their respective applications. In clinical diffusion-weighted MR imaging, the b value is generally altered by changing the strength of the diffusion gradients.( Koh and Collins, 2007)

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