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Expression of e-cadherin and P-cadherin in breast carcinoma histopathological and : Immunohistochemical study / Ahmed Naeem Mohamed Eesa ; Supervised Ahmed Mahmoud Abdelaziz , Samia Mohamed Gabal , Amira Mohamed Bassam

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Ahmed Naeem Mohamed Eesa , 2015Description: 172 P. : facsimiles ; 25cmOther title:
  • فى سرطان الثدى : دراسة نسيجية و مناعية كيميائية (P-cadherin)و بى - كادهريرين(E-cadherin) التعبير عن اي-كادهيرين [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine- Department of Pathology Summary: This study aims to correlate immunohistochemical expression of P- cadherin and E-cadherin with pathological features of breast carcinoma in addition to correlation with estrogen and progesterone receptors status and expression of Her2-neu oncoprotein. The retrospective study was conducted on 50 cases of female patients with breast cancer, admitted to Kasr Al-Ainy hospital where their paraffin blocks and copies of their pathology reports were available (From January 2012 to December 2012). All cases were treated with modified radical mastectomy with complete dissection of axillary lymph nodes. Immunohistochemical staining for each case was conducted for both E-cadherin and P-cadherin. As regards expression of E-cadherin , 38 (76 %) cases were positive for E-cadherin (expressed), while 12 (24 %) cases were negative (not expressed). As regards expression of P-cadherin , 38 (76 %) cases were positive for P-cadherin (expressed), while 12 (24 %) cases were negative (not expressed)
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.27.Ph.D.2015.Ah.E (Browse shelf(Opens below)) Not for loan 01010110066611000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.27.Ph.D.2015.Ah.E (Browse shelf(Opens below)) 66611.CD Not for loan 01020110066611000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine- Department of Pathology

This study aims to correlate immunohistochemical expression of P- cadherin and E-cadherin with pathological features of breast carcinoma in addition to correlation with estrogen and progesterone receptors status and expression of Her2-neu oncoprotein. The retrospective study was conducted on 50 cases of female patients with breast cancer, admitted to Kasr Al-Ainy hospital where their paraffin blocks and copies of their pathology reports were available (From January 2012 to December 2012). All cases were treated with modified radical mastectomy with complete dissection of axillary lymph nodes. Immunohistochemical staining for each case was conducted for both E-cadherin and P-cadherin. As regards expression of E-cadherin , 38 (76 %) cases were positive for E-cadherin (expressed), while 12 (24 %) cases were negative (not expressed). As regards expression of P-cadherin , 38 (76 %) cases were positive for P-cadherin (expressed), while 12 (24 %) cases were negative (not expressed)

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