Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis

Assessment of liver fibrosis stage is important in determining the prognosis and treatment strategy in chronic liver diseases. To overcome the limitations of liver biopsy, great efforts have been made to develop and validate noninvasive methods for detecting liver fibrosis, including serological indicators and imaging methods. Among these noninvasive methods, ultrasound-based elastography techniques are increasingly employed to assess parenchymal stiffness. Real-time elastography is a rapidly evolving technique that can reveal the elastic properties of tissues, and display it as real time colored images. Liver fibrosis index (LFI) is a new quantitative method with high correlation with liver fibrosis stage. This technique can avoid unnecessary invasive liver biopsy, however, it should be cautiously applied to everyday clinical practice

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