Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of General Surgery

For more than a century, clinicians have attempted to use fat for the treatment of tissue deficiencies and contour abnormalities with variable outcome and fate of the transferred fat.Autologous fat transfer for facial contouring has become popular in plastic surgery only in the past 20 years.In fact, surgeons have understood that ageing of the face is not attributable to gravity-induced ptosis alone, but is also a consequence of volume loss caused by tissue atrophy. Thus, volume replacement using fat transfer is the aim of the hereby presented treatment.The aim of this study is to evaluate the effect of two types of isolation of lipograft in the face and their persistence and the changes they will produce.This study was conducted on 50 patients complaining of facial ageing and facial scars whether post traumatic or post burn from the period betweenJanuary 2013 and December 2014 The sample population was divided into two groups:Group A underwent fat processing using the mechanical mesh/gauze to separate the SVF (39 patients) in order to obtain micro and nanofat grafts. Group B underwent fat processing using the enzymatic /collagenase technique to separate the SVF (11 patients).The techniques of fat processing both the mechanical and enzymatic techniques have demonstrated valuable clinical outcomes in all indications. Although the enzymatic technique demonstrated valuable results in concentrating the ADSC{u2019}s with less need for secondary retouches

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