Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of General Surgery

Background: Neoadjuvant chemotherapy for breast cancer was originally used in locally advanced inoperable disease in order to achieve surgical resection. It was then extended to operable breast cancer with a view to down staging tumours to facilitate breast-conserving surgery. Increasingly, it is being considered as a treatment for earlier-stage disease. Methods: A retrospective study, discussing outcome of surgical intervention in breast cancer following neoadjuvant chemotherapy. It was conducted on 35 patients randomly selected from the files of surgical oncology department, in Luxor International Hospital over the last five years. Results: Conclusion: The neoadjuvant therapy is justified in patients with locally advanced breast cancer as they have bigger chance for breast preserving surgery

Issued also as CD