Reparative dentin formation using stem cell therapy versus calcium hydroxide in direct pulp capping : An animal study / Possy Moustafa Abdelaziz Mahmoud ; Supervised Amira Farid Elzoghbi , Mohamed Mostafa Shokry , Ahmed Wael Abozeid

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Possy Moustafa Abdelaziz Mahmoud

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TextLanguage: English Publication details: Cairo : Possy Moustafa Abdelaziz Mahmoud , 2018Description: 116 P. : charts , facsimiles ; 25cmOther title:

تكوين العاج السني الاصلاحي باستخدام الخلايا الجذعيه مقارنه بهيدروكسيد الكالسيوم للتغطيه المباشره للب السني [Added title page title]

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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Operative Dentistry Summary: 1.The aim of the study: The aim of the study was to investigate the potential of dental pulp stem cells (DPSCs) to promote normal dentin tissue formation compared to calcium hydroxide in direct pulp capping procedures. Subjects and methods: A total number of three mongrel dogswere used as experimental animal models. Two access cavities were prepared in each dog and the pulp tissue was extirpated.The extirpated pulp tissues were digested to obtain single-cell suspensions. In each of the three dogs, class V cavities were prepared and the pulp exposed, followed by capping:Group I: (12 teeth) pulp capping with calcium hydroxide (Dycal).Group II: (12 teeth) pulp capping with dental pulp stem cells (DPSCs).Results: Histologically, the reparative dentin formed in the calcium hydroxide group exhibited a mixed dentin structure with both amorphous (atubular) and tubular dentin. Tunnel defects were also observed within the formed reparative dentin. In dental pulp stem cells group, DPSCs formed normal dentin structure that was similar to normal secondry dentin in terms of less organized dentinal tubules

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Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.09.03.Ph.D.2018.Po.R (Browse shelf(Opens below))		Not for loan	01010110077983000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.09.03.Ph.D.2018.Po.R (Browse shelf(Opens below))	77983.CD	Not for loan	01020110077983000

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Thesis (Ph.D.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Operative Dentistry

1.The aim of the study: The aim of the study was to investigate the potential of dental pulp stem cells (DPSCs) to promote normal dentin tissue formation compared to calcium hydroxide in direct pulp capping procedures. Subjects and methods: A total number of three mongrel dogswere used as experimental animal models. Two access cavities were prepared in each dog and the pulp tissue was extirpated.The extirpated pulp tissues were digested to obtain single-cell suspensions. In each of the three dogs, class V cavities were prepared and the pulp exposed, followed by capping:Group I: (12 teeth) pulp capping with calcium hydroxide (Dycal).Group II: (12 teeth) pulp capping with dental pulp stem cells (DPSCs).Results: Histologically, the reparative dentin formed in the calcium hydroxide group exhibited a mixed dentin structure with both amorphous (atubular) and tubular dentin. Tunnel defects were also observed within the formed reparative dentin. In dental pulp stem cells group, DPSCs formed normal dentin structure that was similar to normal secondry dentin in terms of less organized dentinal tubules

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