Some pharmacological and toxicological studies on some constituents of apricot seeds / Aya Abdelsalam Aboelola Shokry ; Supervised Gehan Mohamed Kamel , Nagwa Elsayed Ahmed Awad

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Aya Abdelsalam Aboelola Shokry

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TextLanguage: English Publication details: Cairo : Aya Abdelsalam Aboelola Shokry , 2018Description: 188 P. : charts ; 25cmOther title:

بعض الدراسات الفارماكولوجية والسمية علي بعض مكونات بذور المشمش [Added title page title]

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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Veterinary Pharmacology Summary: The present study aimed to investigate some phytochemical, toxicological and pharmacological activities of ethanolic apricot seeds extracts. Different phytochemicals were analyzed. The phytochemical screening was done for determination of total phenolic compounds by Folin{u2013}Ciocalteu method, total flavonoids by aluminum chloride colorimetric method, total carotenoids by colorimetric method and amygdalin content by using HPLC. The anti-inflammatory activity and total antioxidant capacity of the extracts were done. The anti-inflammatory activity was done in vitro by determination of the half maximal inhibitory concentration (IC50) values for inhibition of the enzymes cyclooxygenase 1, 2 (COX-1, COX-2). The total antioxidant capacity was determined by determination of DPPH (1, 1-diphenyl-2-picryl-hydrazyl) radical scavenging activity. The in-vitro cytotoxicity of extracts on normal human lung cell line and liver cancer cells (HepG2) was determined. The toxicological studies (Acute toxicity) of 70% and 99.9% ethanolic extracts were investigated

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Item type	Current library	Home library	Call number	Copy number	Status	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.10.15.M.Sc.2018.Ay.S (Browse shelf(Opens below))		Not for loan	01010110078097000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.10.15.M.Sc.2018.Ay.S (Browse shelf(Opens below))	78097.CD	Not for loan	01020110078097000

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Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Veterinary Pharmacology

The present study aimed to investigate some phytochemical, toxicological and pharmacological activities of ethanolic apricot seeds extracts. Different phytochemicals were analyzed. The phytochemical screening was done for determination of total phenolic compounds by Folin{u2013}Ciocalteu method, total flavonoids by aluminum chloride colorimetric method, total carotenoids by colorimetric method and amygdalin content by using HPLC. The anti-inflammatory activity and total antioxidant capacity of the extracts were done. The anti-inflammatory activity was done in vitro by determination of the half maximal inhibitory concentration (IC50) values for inhibition of the enzymes cyclooxygenase 1, 2 (COX-1, COX-2). The total antioxidant capacity was determined by determination of DPPH (1, 1-diphenyl-2-picryl-hydrazyl) radical scavenging activity. The in-vitro cytotoxicity of extracts on normal human lung cell line and liver cancer cells (HepG2) was determined. The toxicological studies (Acute toxicity) of 70% and 99.9% ethanolic extracts were investigated

Issued also as CD

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