Effect of various stabilizers on efficacy of live attenuated brucella RB51 vaccine / Sally Magdy Abdelsalam Abdelhamid ; Supervised Khaled Farouk Elamry , Khaled Abdelkader Abdelazeem , Ahmed Samir Mohamed
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TextLanguage: English Publication details: Cairo : Sally Magdy Abdelsalam Abdelhamid , 2019Description: 94 P. : charts ; 25cmOther title: - تاثير المثبتات المختلفة علي كفاءة لقاح البروسيلا اربي51 [Added title page title]
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Thesis
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قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.10.10.Ph.D.2019.Sa.E (Browse shelf(Opens below)) | Not for loan | 01010110079170000 | ||
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مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.10.10.Ph.D.2019.Sa.E (Browse shelf(Opens below)) | 79170.CD | Not for loan | 01020110079170000 |
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Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Microbiology
Brucellaabortusstrain RB51 is a cattle vaccine that is approved for use in the U.S. for prevention of brucellosis. At the present time,Egypt is considering the use of SRB51 vaccine in their brucellosis control programs. In the current study, the effect of five stabilizing media, on the viability of lyophilized SRB51 over a 52 week period and the characteristics of the immune responses triggered by vaccination with locally prepared RB51 vaccine are determined. 5 groups of mice immunized with the prepared RB51 vaccines and subsequently challenged with high virulent B.abortus544 were protected from reinfection. Post vaccination, the early production of gamma interferon seems to have the prominent role in inducing an immunologically based protection
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