Relationship between SP-C gene codon 186 polymorphism (rs1124) and respiratory distress syndrome in premature neonates / Shaimaa Ramadan Korany Menieseer ; Supervised Iman Ahmed Ehsan Abdelmeguid , Eman Abdelghany Abdelghany , Nouran Mohamed Nabil Momen

By:

Shaimaa Ramadan Korany Menieseer

Contributor(s):

Material type: Text

TextLanguage: English Publication details: Cairo : Shaimaa Ramadan Korany Menieseer , 2019Description: 106 P. : charts , facsimiles ; 25cmOther title:

ومتلازمة الضائقة التنفسية في الأطفال المبتسرين (rs1124) كودون 186SPC العلاقة بين تعدد أشكال الجين [Added title page title]

Subject(s):

Online resources:

Click here to access online

Available additional physical forms:

Issued also as CD

Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: Background: Respiratory distress syndrome (RDS) of the newborn is the most common cause of morbidity and mortality. Its pathophysiology is complex, In addition to environmental factors; genetic factors may participate in RDS risk. Aims: To assess potential association of SP-C gene rs1124 polymorphism with RDS development and severity in a group of Egyptian preterm newborns. Methods: One hundred preterm neonates were enrolled in a prospective case control study. 50 neonate s were with RDS and 50 neonates as a control group. Detailed history and clinical examination data were recorded. Respiratory distress (RD) was scored according to Downes{u2019} scoring system. Genotyping was performed by PCR-RFLP method. Results: There were no statistical significant difference in GG, AG &AA genotypes or A & G alleles frequencies of SFTPC rs1124 among RDS neonates and controls. Also there were no statistical significant differences of genotyping frequencies and severity of RDS. Decreased gestational age was the most important factors in predisposition to RDS. Conclusion: No association of SP-C gene rs1124 polymorphism with RDS development and severity of the disease in Egyptian preterm newborns

Tags from this library: No tags from this library for this title. Log in to add tags.

Average rating: 0.0 (0 votes)

Holdings
Item type	Current library	Home library	Call number	Copy number	Status	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.28.M.Sc.2019.Sh.R (Browse shelf(Opens below))		Not for loan	01010110079367000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.28.M.Sc.2019.Sh.R (Browse shelf(Opens below))	79367.CD	Not for loan	01020110079367000

Browsing المكتبة المركزبة الجديدة - جامعة القاهرة shelves Close shelf browser (Hides shelf browser)

Previous	No cover image available	No cover image available	No cover image available	No cover image available	No cover image available	No cover image available	No cover image available	Next
Previous	Cai01.11.28.M.Sc.2019.Sh.E Effect of adherence to a nutritional bundle protocol on reducing necrotizing enterocolitis in preterm infants /	Cai01.11.28.M.Sc.2019.Sh.O Oxygen therapy as a risk factor for developing necrotizing enterocolitis in preterm infants /	Cai01.11.28.M.Sc.2019.Sh.O Oxygen therapy as a risk factor for developing necrotizing enterocolitis in preterm infants /	Cai01.11.28.M.Sc.2019.Sh.R Relationship between SP-C gene codon 186 polymorphism (rs1124) and respiratory distress syndrome in premature neonates /	Cai01.11.28.M.Sc.2019.Sh.R Relationship between SP-C gene codon 186 polymorphism (rs1124) and respiratory distress syndrome in premature neonates /	Cai01.11.28.M.Sc.2019.Sh.U Urinary neutrophil gelatinase associated lipocalin (ngal) as a biomarker for diagnosis of diabetic nephropathy in type-1 diabetes mellitus /	Cai01.11.28.M.Sc.2019.Sh.U Urinary neutrophil gelatinase associated lipocalin (ngal) as a biomarker for diagnosis of diabetic nephropathy in type-1 diabetes mellitus /	Next

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Background: Respiratory distress syndrome (RDS) of the newborn is the most common cause of morbidity and mortality. Its pathophysiology is complex, In addition to environmental factors; genetic factors may participate in RDS risk. Aims: To assess potential association of SP-C gene rs1124 polymorphism with RDS development and severity in a group of Egyptian preterm newborns. Methods: One hundred preterm neonates were enrolled in a prospective case control study. 50 neonate s were with RDS and 50 neonates as a control group. Detailed history and clinical examination data were recorded. Respiratory distress (RD) was scored according to Downes{u2019} scoring system. Genotyping was performed by PCR-RFLP method. Results: There were no statistical significant difference in GG, AG &AA genotypes or A & G alleles frequencies of SFTPC rs1124 among RDS neonates and controls. Also there were no statistical significant differences of genotyping frequencies and severity of RDS. Decreased gestational age was the most important factors in predisposition to RDS. Conclusion: No association of SP-C gene rs1124 polymorphism with RDS development and severity of the disease in Egyptian preterm newborns

Issued also as CD

There are no comments on this title.

to post a comment.

Click on an image to view it in the image viewer