Thesis (Ph.D.) - Cairo University - Faculty of African Postgraduate Studies - Department of Natural Resources

An epidemiological studies on fascioliasis was undertaken from May 2017 to April 2018. Prevalence among cows, sheep, goats and humans were investigated. Factors relating to the spread, control and prevention in Northern Bauchi state, Northeastern Nigeria were also documented. A set of 7640 stool and 7640 random bile samples were collected from slaughtered ruminants at the seven local abattoirs of northern Bauchi state. Systematic sampling was also employed to obtain 400 stool samples from patients who visited a centrally placed hospital. Stool and bile samples were analyzed using formol ether concentration technique. Semi structured questioneers were also administered to 400 adults above the age of 20. Laboratory assessment of the molluscicidal potency of crude seed oil of Azadrachta indica, Acacia albida and Balanite aegyptiaca was conducted as a possible control strategy. An overall prevalence of 40.5% was recorded with significant difference between localities, species, sex and age (p=0.0005). A prevalence of 3.5% among patients was observed with significant difference between sexes. Level of awareness on fascioliasis was generally low. All the three plant species seed oils tested showed various levels of molluscicidal potency; as recorded in A. indica with LC50 values of 6.328 and LC90 values of 7.925 while a relatively low molluscicidal potency was observed in A. albida and B. aegyptiaca with similar LC50 values of 14.348 and LC90 values of 17.475 respectively. Public awareness campaigns, meat inspection and reduction of the population of intermediary snail host using environment friendly molluscicides were recommended

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