Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Operative Dentistry

The study aim was to evaluate the retention rate of Hydroxyapatite Nanofiber reinforced flowable composite compared to conventional resin-based flowable composite during management of initial non cavitated pits and fissures carious lesion in adult population over a one-year period. A total of 19 volunteer patients ranging in age from 18 to 28 years, diagnosed with at least 2 non-cavitated pit-and-fissure caries in the first and second molars were selected for this randomized split-mouth design trial. A total of 38 sealants, were placed. The teeth were sealed with NovaPro{u2122} Flow Hydroxyapatite Nanofiber reinforced flowable composite in one side, while Filtek{u2122} Z350 XT Flowable conventional resin-based composite on the contralateral. Each restoration was independently evaluated in terms of retention rate at 1, 6, and 12 months. Data were analyzed using Wilcoxon signed-rank test and Friedman{u2019}s test at p < 0.05. The Results showed that NovaPro{u2122} Flow Hydroxyapatite showed complete retention with 100% at 1, 6, month evaluation periods, while Filtek{u2122} Z350 XT retention rates were 100%, 78.9%, respectively, for the same evaluation periods. At the 12-month recall, 2 (10.5%) total losses were observed in subjects treated with NovaPro{u2122} Flow and 2 total losses (15.8%) for Filtek{u2122} Z350 XT. No statistical significant difference in the retention rate in both sealants during different follow-up intervals (P>0.05) Conclusions: The retention rate of both hydroxyapatite nanofibers reinforced flowable resin composite and the conventional nanofilled flowable resin composite after one year of follow up was comparable. Clinical relevance: The clinical survival rate of both tested materials may indicate them as effective approaches for preventing carious lesions in permanent teeth

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