Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Background: Pneumonia is a major cause of childhood morbidity and mortality worldwide, some congenital heart diseases (CHD) that cause increased pulmonary blood flow is a common predisposing factor for pneumonia in children. Aim of work: to identify the most common organisms causing bacteremia in cases of pneumonia with and without congenital heart disease and study any role of congenital heart disease affecting type of bacteremia in pneumonia Materials and methods: A prospective study conducted at Pediatric Hospital, Cairo university on 55 children with pneumonia and 55 children with pneumonia and congenital heart disease, CXR, CBC differential, CRP, and blood cultures were done for all patients and comparative results were evaluated.Results: In pneumonia group 24 cases (43.6%) blood culture results showed no growth, 11 cases (20%) reported klebsiella growth, 6 cases (10.9%) CONS, 4 cases (7.3%) MRSA, 2 cases (3.6%) Candida, 2 cases (3.6%) Pseudomonas in comparison to CHD group 34 cases (61.8%) showed no growth, 10 cases (18.2%) reported klebsiella, 5 cases (9.1%) reported CONS, 3 cases (5.5%) reported Candida but no statistically significant difference found. Conclusion: Frequency of bacteremia in children with pneumonia with and without congenital heart disease were not significantly different, the most common organism causing bacteremia in cases of pneumonia with or without congenital heart disease is klebsiella and the most sensitive antibiotic is polymyxin B

Issued also as CD