Sally Ashraf Mohamed Asker, <br/><br/>
Neurodevelopmental outcomes of singleton conceived from fresh and frozen embryo transfer compared with naturally conceived / 
 / التطور العصبي للمولود الفردي الناتج من الأجنة الحديثة والأجنة المجمدة مقارنة بالحمل الطبيعي  
by Sally Ashraf Mohamed Asker ; Supervisors Prof. Dr. Naglaa Ahmed Zaky, Prof. Dr. Faten Hassan Abdelazeim, Prof. Dr. Alaa Wageh Osman. 
 - 169 pages :  illustrations ;  25 cm. +   CD. 
<br/><br/>Thesis (Ph.D)-Cairo University, 2023. 
<br/><br/>Bibliography: pages 140-162. 
<br/><br/> Background: Assisted Reproductive Technologies were first developed nearly four <br/>decades ago to aid in reducing the burden of infertility. Today, Assisted Reproductive <br/>Technologies is accountable for greater than 4 percent of all live births. While most of <br/>Assisted Reproductive Technologies-born infants are healthy, concerns about the <br/>health of Assisted Reproductive Technologies born infants have emerged recently. <br/>There is an elevated risk of perinatal negative outcome in newborns conceived by <br/>Assisted Reproductive Technologies. Purpose: The purpose of this study was to <br/>compare the neurobehavior and maturity of singleton neonates conceived through <br/>fresh and frozen embryo transfer with those through naturally conceived. Methods: <br/>This study included186 singleton neonates whose mothers age ranged from 25 to 35 <br/>years old with their body mass index ranged from 18.5 to 29 and they were born <br/>through in vitro fertilization/ intra cytoplasmic injection (frozen embryo transfer and <br/>fresh embryo transfer) following 37 weeks of gestation were enrolled in this study. <br/>Singleton neonates conceived without fertility treatments (natural conceived) served <br/>as a reference group. They were equally distributed into three groups: Group A: 62 <br/>Naturally conceived singleton neonates, Group B: 62 singleton neonates conceived <br/>from fresh embryo transfer and Group C: 62 singleton neonates conceived from <br/>frozen embryo transfer. Singleton neonates in each three groups were assessed for <br/>behavior by Brazelton Neonatal Behavioral Assessment Scale and for maturity by <br/>New Ballard Score. Results: The Brazelton and New Ballard score demonstrated <br/>significant differences between three groups P values <0.05. Conclusion: The <br/>neurobehavior of singleton neonates conceived from naturally conceived are better <br/>than that of fresh and frozen embryo transfer and the estimated gestational age was <br/>lowest in fresh embryo transfer in comparison with both frozen embryo transfer and <br/>normal conceived and it was lower in normal conceived compared to frozen embryo <br/>transfer.   شملت الدراسة ١٨٦ مولود فردي لاجنة حديثة ومجمدة وحمل طبيعي، تم توزيع المواليد الذين تم ولادتهم بعد ٣٧ أسبوع  وعمر أمهاتهم يتراوح بين ٢٥ الي ٣٥ سنة و معدل كتلة الجسم للامهات يتراوح من١٨,٥ الي ٢٩ علي ثلاثة مجموعات .المجموعة ا :٦٢ مولود فردي ناتج عن حمل طبيعي المجموعة ب : ٦٢مولود فردي ناتج من اجنة حديثة ⸲ المجموعة ج : ٦٢ مولود فردي ناتج من اجنة مجمدة. كل مولود في الثلاث مجموعات تم تقييمه بمقياس "برازيلتون" لتقييم السلوك العصبي ومقياس "بالرد" الحديث لتقييم النضج . السلوك العصبي للمولود الناتج عن الحمل الطبيعي افضل من الناتج عن الاجنة الحديثة و المجمدة و عمر الحمل التقريبي في المولود الفردي الناتج من اجنة حديثة اقل من الناتج عن الاجنة المجمدة و حمل طبيعي و اقل في المولود الناتج من حمل طبيعي مقارنة بالاجنة المجمدة 
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<br/><br/><br/>Text in English and abstract in Arabic & English. 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Physical Therapy
<br/><br/><label>Subjects--Index Terms: </label>Fresh and frozen embryo  Neurologic morbidity in Assisted Reproductive Technologies offspring  Estimated gestational age  New Ballard Score 
<br/><br/><label>Dewey Class. No.: </label>615.82