TY - BOOK AU - Shimaa Mostafa Ayoub, AU - Mohamed Barakat Mostafa AU - Ahmed Ismael Abdelgalil TI - Feline lower urinary tract diseases U1 - 636.089 PY - 2024/// KW - Veterinary diseases KW - qrmak KW - Cat KW - Urinary KW - Feline KW - FLUTD KW - Hypocalcemia N1 - Thesis (M.Sc)-Cairo University, 2024; Bibliography: pages 56-69; Issues also as CD N2 - Feline lower urinary tract disease (FLUTD) is a frequent feline condition mostly affects urethra and/or bladder. This study aimed to characterize clinical markers, diagnose distinct FLUTD problems, and perform urine, hematologic, biochemical analysis, bacterial culture, and stone analysis on different FLUTD groups. Abdominal radiography and ultrasonography findings were included. The efficacy of medical and surgical treatments for FLUTD and urethral blockages in cat populations was assessed. A total of 56 cats (7 females and 49 males) admitted with typical observations of FLUTD were involved into the study. Urolithiasis (37.5%) was the most often identified form of urinary tract disease (FLUTD), with urethral plugs (10.7%), feline idiopathic cystitis (FIC) (33.9%), bacterial UTI (14.2%), and neoplasia (3.5%) following closely behind. Cats with urolithiasis, urethral plugs, and FIC were more likely to experience urethral blockage (42.8%). Samples of urine were collected by cystocentesis or catheterization. Urinary analysis had non-significant variations in urine pH and specific gravity. The level of RBCs in urine sample is high in urolithiasis, urethral plugs and FIC groups with marked significant (P<0.05) hematuria. Pyuria was higher in urinary tract infection (25.42±15.3) and urolithiasis (20.53±10.02) with significant (P<0.05) increase in numbers of WBCs (P< 0.05). Significant (P< 0.01) higher amount of struvite amorphous crystalluria in the urine sediment in urolithiasis (71.4%) and FIC (68.4%) was reported. E-coli, Proteus and Staphylococcus species were the isolated bacteria in UTI. The appropriate feline antimicrobials bacterial culture and sensitivity test were Amoxicillin/clavulanic and ciprofloxacin. Dissolution therapy was recommended in struvite and urate uroliths for control uroliths reformations. Thickening urinary bladder wall and pedunculated or non-pedunculated bladder mass located in the dorsal margin of the bladder projecting in the bladder lumen suggesting neoplasia in two male Egyptian Mau cats. The clinic-pathological findings, the adopted serial diagnostic tools, protocol of treatment would be a useful information for management, reduce the incidence of the uroliths conditions and encourage the veterinarian successful control and treatment of FLUTD. Serum chemistry abnormalities that widely observed were post-renal azotemia with increase in creatinine and BUN levels mainly in UO, FIC and urethral plugs. Hypocalcemia, hypophosphatemia and hyperkalemia were the most common findings within FLUTD groups. Positive correlations were documented between potassium, BUN and creatinine concentrations in serum. Negative correlations were documented between serum calcium (Hypocalcemia) and phosphorus (hypophosphatemia) and serum creatinine and BUN. Decompressive cystocentesis, urethral catheterization, placement of an indwelling catheter and I/V electrolytes were effective in relief of urethral obstruction, correct hypovolemia, hyperkalemia and promote renal excretion of potassium; تقدم هذه الدراسة معلومات عن أمراض المسالك البولية السفلية لدى القطط في مصر. كانت الأسباب الأكثر شيوعًا لأمراض المسالك البولية السفلية هي الحصوات البوليه (37.5٪)، يليه التهاب المثانة مجهول السبب (FIC) (33.9٪)، وعدوى المسالك البولية البكتيرية (UTI) (14.2٪)، وسدادات مجرى البول (10.7٪) والأورام ( 3.5%). كان انسداد مجرى البول (42.8٪) وأكثر شيوعًا في القطط المصابة بحصوات مجرى البول وسدادات مجرى البول و FIC. وكان العمر والسلالة والجنس والاقامه فى المنزل والتغذية هي عوامل الخطر الأكثر شيوعا لتطوير أمراض المسالك البولية السفلية. كانت هناك كمية كبيرة (0.01