Emad Eldeen Mohamed Hassan Ahmed, <br/><br/>
The effect of sleep disorders on postural control in patients with multiple  sclerosis /  Remainder of title /  
 تأثير اضطرابات النوم على الاتزان فى مرضى التصلب المتعدد / 
By Emad Eldeen Mohamed Hassan Ahmed; Under Supervision of Prof. Dr. Wael Salah Shendy, Prof. Dr. Amr Hassan Alhusseiny, Dr. Amina Awad 
 - 84 pages :   illustrations ;   25 cm. +   CD. 
<br/><br/>Thesis (M.Sc.)-Cairo University, 2024.  
<br/><br/>Bibliography: pages 200-250. 
<br/><br/> Background: Sleeping disorders are more common in people with MS than in <br/>healthy people. Sleep deprivation for one-night, chronic low-quality sleep, and <br/>sleep disorders were all found to affect normal healthy adults' postural control and <br/>balance abilities. There is a knowledge gap in understanding the impact of sleep <br/>disorders on physical performance in people with MS and in normal subjects. <br/>Aim of the study: To investigate the effect of sleep disorders on postural control <br/>in patients with remitting-relapsing multiple sclerosis (RRMS). <br/>METHODS: A cross-sectional observational study was conducted on sixty <br/>RRMS patients of both sexes, aged 20 to 40 years, with EDSS scores less than <br/>four and greater than 24, according to the Mini-Mental State Examination Scale <br/>(MMSE). Patients were divided according to the Pittsburgh sleep quality index <br/>(PSQI) into two groups; the sleep disorders group (SD group, n=30, PSQI > 5) and <br/>the non-sleep disorder group (NSD group, n=30, PSQI ≤ 5). <br/>Sleep was assessed using the PSQI and the Epworth sleepiness scale (ESS). In <br/>contrast, postural control was evaluated by the Biodex Balance System by the <br/>dynamic test measurements of overall stability index (SI), anteroposterior stability <br/>index (APSI), mediolateral stability index (MLSI), and Limits of stability (LOS). <br/>Fatigue was assessed using the fatigue severity scale. <br/>Results: There is no significant difference between the two groups in the Epworth <br/>sleepiness scale, overall SI, and the APSI, while there was a substantial difference <br/>in the fatigue severity scale, MLSI, and the LOS in favor of the SD group. <br/>Conclusion: These results revealed that sleeping disorders in RRMS may <br/>negatively affect some aspects of their postural control, mainly mediolateral <br/>stability and limits of stability, and negatively affect fatigue.   أجريت دراسة رصدية مقطعية مستعرضة على ستين مريضا  يعانون من  التصلب المتعدد الانتكاسي من كلا الجنسين ، تتراوح أعمارهم بين العشرون و الاربعون عاما , مع درجة مقياس حالة الإعاقة الموسع  أقل من أربعة .  ودرجة أكبر من اربعة وعشرون وفقا لمقياس فحص الحالة العقلية المصغر .   تم تقسيم المرضى وفقا لمؤشر جودة النوم في بيتسبرغ إلى مجموعتين. مجموعة اضطرابات النوم (عدد= ثلاثون ، > 5 مؤشر جودة النوم في بيتسبرغ) ، ومجموعة اضطرابات غير النوم (عدد= ثلاثون ، 5 ≤ مؤشر جودة النوم في بيتسبرغ).   تم تقييم النوم باستخدام مؤشر جودة النوم في بيتسبرغ ومقياس إيبوورث للنعاس  ، بينما تم تقييم التحكم في الوضع من خلال نظام توازن بيودكس من خلال قياسات الاختبار الديناميكي لمؤشر الاستقرار الكلي ومؤشر الاستقرار الأمامي الخلفي  ومؤشر الاستقرار المتوسط وحدود الاستقرار. تم تقييم التعب باستخدام مقياس شدة التعب.   
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<br/><br/><br/>Text in English and abstract in Arabic & English. 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Physical Therapy
<br/><br/><label>Subjects--Index Terms: </label>Multiple sclerosis  sleep disorders  postural control  balance 
<br/><br/><label>Dewey Class. No.: </label>615.82