TY  - BOOK
AU  - Fatima Abdelhamid Youssef,
AU  - Ahmed Hussein Khalil
AU  - Amir Kamal
AU  - Mohamed Fathy ElShal
TI  - Efficacy of reinforcement of staple line by glue vs non-reinforcement on leakage post laparoscopic sleeve gastrectomy for obese patients
U1  - 617.553 
PY  - 2025///
KW  - Gastrectomy
KW  - تكميم المعدة
KW  - Sleeve gastrectomy postoperative leakage
KW  - staple line reinforcement
KW  - nebulized cyanoacrylate glue
KW  - bariatric surgery
KW  - complication
KW  - تقوية حواف المعدة
N1  - Thesis (M.Sc)-Cairo University, 2025; Bibliography: pages 69-83.; Issues also as CD
N2  - Background: Sleeve gastrectomy is a widely performed bariatric procedure, but 
postoperative staple line leakage remains a significant complication, leading to 
increased morbidity and healthcare costs. Various techniques have been 
explored to reinforce the staple line, yet an optimal solution remains elusive. 
nebulized cyanoacrylate glue , a novel surgical adhesive, has shown promise in 
preliminary studies for its ability to enhance tissue sealing and reduce 
complications. 
Objectives: This study aims to evaluate the effectiveness of nebulized 
cyanoacrylate glue in reinforcing the staple line during sleeve gastrectomy and 
its impact on reducing postoperative leakage rates. Additionally, it seeks to 
assess its influence on operative time, length of hospital stay, and overall 
postoperative complications. 
Methods: A prospective Randomized Controlled Clinical Trial was conducted 
involving 70 patients undergoing sleeve gastrectomy. Participants were divided 
into two equal groups: one without staple line reinforcement and the other 
utilizing nebulized cyanoacrylate glue in reinforcement of staple line. Data were 
collected on intraoperative parameters, postoperative leakage rates, hospital stay 
duration, and other complications. Statistical analysis was performed to compare 
outcomes between the two groups. 
Results: The nebulized cyanoacrylate glue group demonstrated a statistically 
no significant reduction in postoperative staple line leakage rates compared to 
the Non reinforcement group. The findings suggest that the choice between two 
methods does not significantly impact the incidence of leakage. 
Conclusion: No statistically difference in post-operative leakage rate between 
the glue-reinforced and non-reinforced groups. Both groups have similar 
outcomes in terms of bleeding, hospital stay duration, and readmission rates. 
These findings suggest that glue reinforcement of staple line does not provide a 
significant advantage in preventing staple line leakage over non-reinforcement.; تعد جراحة تكميم المعدة من اقصر عمليات السمنه انتشارا. المضاعفات ما بعد عمليات السمنة ومنها جراحة تكميم المعدة تؤثر بشكل كبير على صحة المريض وكذلك عبئا على المنظومة الصحية. وسائل مختلفة تم اقتراحها لتقوية حواف المعدة المكممة لتقليل التسريب ما بعد الجراحة ولكن ما زالت هذه الوسائل تحت الدراسة حتى يتم الوصول لحل مناسب لتقليل التسريب. يعتبر الصمغ الجراحى من احدى هذه الوسائل التى يتم دراستها الان بعد ما اظهر فاعليته على بعض الجروح. وتهدف هذه الدراسة الى معرفة مدى تأثير الضمغ الجراحى على تقليل حالات المعدة المقننة وتوضح مدى تأثيره على تقليل نسبة التسريب بعد عمليات التكميم
ER  -