TY - BOOK AU - Hala Bakr Ali Elnassan AU - Mervat Mostafa Elenany , AU - Mona Monir Kamel , AU - Omneya Mahmoud Khalil , TI - Computer-based drug design and synthesis of certain pyrazolopyrimidine and bis(pyrimidinyI) methane derivatives as potential antineoplastic agents / PY - 2009/// CY - Cairo : PB - Hala Bakr Ali Elnassan , KW - Antineoplastic activity KW - Bis(6-aminopyrimidin-5-y1) (substituted pheny1) methane KW - Pyrazolo[3,4-d] pyrimidin-4-one N1 - Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Organic chemistry; Issued also as CD N2 - The study comprises a survey on the cyclin dependent kinases(CDKs) and their inhibtors.The thesis involves the design docking study and synthesis of some pyrazolo[3,4-d] pyrimidin-4-one,pyrazolo[1,5-a] pyrimidine and bis(6-aminopyrimidin-5-y1) (substituted pheny1) methane derivatives as CDK2 inhibitors to be investigated as new antineoplastic agents UR - http://172.23.153.220/th.pdf ER -