Nesrine Abdelrehim Elgohary <br/><br/>
Potentiometric determination of sibutramine using batch and flow injection analysis /  
Nesrine Abdelrehim Elgohary ; Supervised Rasha Elnashar 
 - Cairo :   Nesrine Abdelrehim Elgohary ,   2009 
 - 140 Leaves :   charts ;   30cm 
<br/><br/>Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Analytical Chemistry 
<br/><br/> Sibutramine a synthetic compound for the treatmentof obesity is a centrally acting serotonin - norepinephrine reuptake inhibitor structurally related to amphetamines . The present work offers an ion - selective electrode of the plastic membrane type for the determination of sibutramine hydrochloride monohydrate (SBT) . The electrode depends mainly on the incorporation of the ion - associate of the above mentioned drug with phosphtungestic acid (PTA) in a PVC matrix