Nermine Shawki Kamal  <br/><br/>
Value of bone resorption markers to predict skeletal related events and response to bisphosphonate therapy in patients with bone metastases :   A prspective randomized study /  
 قيمة دلالات اورام تأكل العظام لمعرفة تأثيرها على العظام ومدى استجابتها البيسفوسفونات على علاج مرضى الاورام السرطانية المنتشرة بالعظم 
Nermine Shawki Kamal ; Supervised Wafaa Elmetenawy , Hamdy Abdelazim , Emad Hamada 
 - Cairo :   Nermine Shawki Kamal ,   2009 
 - 215P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Oncology (Clinical) 
<br/><br/> The prospective analysis of urinary N - telopeptides collagen break down products type I (NTX) in patients with metastatic bone disease revealed a positive relation between NTX level and risk of Sketal related events (SREs). Normalization of NTX level at 3 months decreases the rate of serious types of SREs (pathological fractures and cord compression) . Zoledronic acid decreases the rate of one or more SREs by four times in patients with elevated NTX levels compared to no Zoledronic acid 
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<br/><br/><label>Subjects--Index Terms: </label>Bone markers  Metastatic bone disease  N - telopeptides