TY  - BOOK
AU  - Mohamed Saleh Mohamed Ali
AU  - Ashraf H. Abadi , 
TI  - Design synthesis and biological evaluation of novel tetrahydro - Ý - carboline derivatives as phosphodiesterase 5 inhibitors / 
PY  - 2009///
CY  - Cairo : 
PB  - Mohamed Saleh Mohamed Ali , 
N1  - Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Science in Organic Chemistry
N2  - PDE5 inhibitors is a large class of compounds that are primarily used to treat erectile dysfunction (MED) as well as having other medical applications . Tadalafil is one of the most potent members among this class despite its efficacy in treatment of MED it only exhibits a modest selectivity of 5 - folds for PDE - 5 compareed PDE - 11 which may be involved in sperm formation motility and\ or other homonal functions
UR  - http://172.23.153.220/th.pdf
ER  -