TY  - BOOK
AU  - Mai Ahmed Saad Zaghloul
AU  - Ahmed Ihab Abdelaziz , 
TI  - Novel anticancer compounds as efficient apoptotic and potential anti - proliferative drugs in genetically modified hepatocellular carcinoma cell models / 
PY  - 2009///
CY  - Cairo : 
PB  - Mai Ahmed Saad Zaghloul , 
N1  - Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Molecular Genetics
N2  - Hepatocellular Carcinoma is one of the severe malignancies with high incidence worldwide as reported to be ranked the sixth most common cancers[2] . Several studies have investigated the underlying pathogenesis of the disease and hypothesized that the interaction between the etiological factors (e.g. HCV, HBV, AFB and cirrhosis [7] and the hepatocytic genes result in functional (imbalance between pro - apoptotic and anti - apoptotic signaling) and structural genomic alterations(loss and gain of chromosomal regions resulting in deletion of tumor suppressor genes e.g, p53 and Rb genes) constituting the basis for HCC pathogenesis [8,44,189]
UR  - http://172.23.153.220/th.pdf
ER  -