TY - BOOK AU - Afaf Ali Atia Elmalah AU - Maha Abdelhakeem , AU - Mohga Mohamed Badran , AU - Suzan Mohamed Abuelmaaty , TI - Synthesis of certain fused thienopyridine derivatives of expected activity against alzheimer's disease / PY - 2010/// CY - Cairo : PB - Afaf Ali Atia Elmalah , KW - Alzheimer's disease KW - Tacrine KW - Thienopyridine derivatives N1 - Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Organic Chemistry; Issued also as CD N2 - A survey covering the methods used for the synthesis of thienopyridine derivatives in addition to their reactions is illustrated . Abrief outline on their medical importance is also given . This thesis involves the preparation of the starting compounds 2- amino - 3- cyanothiophene derivatives {u2161}a-c (scheme 1) . cyclodehydration reaction between the aminocyanothiophenes and the appropriate cyclanone was achieved by using two methods to obtain thienopyridine derivatives {u2162}a-c, IVa-c, {u2164}a-c, {u2165}I, {u2167} and IX(scheme 2- 4) UR - http://172.23.153.220/th.pdf ER -