Rania Salah Abdelaziz <br/><br/>
The role of CD86 and vascular endothelial growth factor in acute myeloid leukemia /  
 دور سى دى 86 وعامل النشوء الوعائى الدموى فى سرطان الدم الميلودى الحاد 
Rania Salah Abdelaziz ; Supervised Magda M. A. Assem , Basma M. Elgamal , Sherine I. Salem 
 - Cairo :   Rania Salah Abdelaziz ,   2009 
 - 212P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Clinical Pathology 
<br/><br/> AML is the most frequent type of leukemia in adult . Recognition and destruction of leukemic blasts by the immune system is of great interest for the development of immuntherapeutic strategies in AML . T- cell activation requires T-cell receptor recognition and binding to major histocompatability complex (MHC) complex/angtigen presented by an antigen-presenting cell (APC) and the binding of ligands for the T - cell costimulatory receptors CD28 and CTLA - 4, ie, CD80/B7 - 1 and CD86/B7 - 2, respectively 
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<br/><br/><label>Subjects--Index Terms: </label>CD80 CD86  Vasclar Endothelial Growth Factor