TY - BOOK AU - Rania Salah Abdelaziz AU - Basma Mostafa Elgamal , AU - Magda Mahmoud A. Assem , AU - Sherine Ibrahim Salem , TI - The role of CD86 and vascular endothelial growth factor in acute myeloid leukemia / PY - 2009/// CY - Cairo : PB - Rania Salah Abdelaziz , KW - CD80 KW - CD86 KW - Vasclar Endothelial Growth Factor N1 - Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Clinical Pathology; Issued also as CD N2 - AML is the most frequent type of leukemia in adult . Recognition and destruction of leukemic blasts by the immune system is of great interest for the development of immuntherapeutic strategies in AML . T- cell activation requires T-cell receptor recognition and binding to major histocompatability complex (MHC) complex/angtigen presented by an antigen-presenting cell (APC) and the binding of ligands for the T - cell costimulatory receptors CD28 and CTLA - 4, ie, CD80/B7 - 1 and CD86/B7 - 2, respectively UR - http://172.23.153.220/th.pdf ER -