Asmaa Mohammed Mahmoud Hussein <br/><br/>
Evaluation of the potential protective effect of L-carnitine on cisplatin induced nephrotoxicity in rats /  
 تقييم التأثير الإفتراضى الوقائي المحتمل لمركب الإل كارنيتين على تسمم الكلى بمركب السيسبلاتين فى الفئران البيضاء 
Asmaa Mohammed Mahmoud Hussein ; Supervised Fatma Abdelhalim Mahmoud , Hanan Hosni Ahmed , Ahmed Abdelrahman Ahmed 
 - Cairo :   Asmaa Mohammed Mahmoud Hussein ,   2011 
 - 122 P. :   charts ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pharmacology 
<br/><br/> Nephrotoxicity has limited the clinical use of cisplatin in 25-30% of patients, even since the first dose. Although the exact mechanism of CP-induced nephrotoxicity is not well understood, several studies have suggested the involvement of oxidative stress in the development of this drug's renal tubule injury. L-carnitine, through its potential possible antioxidant effect, would have a nephro- protective effect against cisplatin-induced nephrotoxicity  
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<br/><br/><label>Subjects--Index Terms: </label>Cisplatin L-carnitine Nephrotoxicity