01716cam a2200265 a 4500003000900000005001700009008004100026040002800067041000800095100003500103245022800138246022200366260005400588300003100642502008900673520046000762530002201222653001401244653001601258653001901274700004301293700004401336700003701380856003301417EG-GiCUC20250223030546.0120130s2011    ua d   f m    000 0 eng d  aEG-GiCUCbengcEG-GiCUC0 aeng0 aAsmaa Mohammed Mahmoud Hussein10aEvaluation of the potential protective effect of L-carnitine on cisplatin induced nephrotoxicity in rats / cAsmaa Mohammed Mahmoud Hussein ; Supervised Fatma Abdelhalim Mahmoud , Hanan Hosni Ahmed , Ahmed Abdelrahman Ahmed15aتقييم التأثير الإفتراضى الوقائي المحتمل لمركب الإل كارنيتين على تسمم الكلى بمركب السيسبلاتين فى الفئران البيضاء  aCairo : bAsmaa Mohammed Mahmoud Hussein , c2011  a122 P. : bcharts ; c25cm  aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pharmacology  aNephrotoxicity has limited the clinical use of cisplatin in 25-30% of patients, even since the first dose. Although the exact mechanism of CP-induced nephrotoxicity is not well understood, several studies have suggested the involvement of oxidative stress in the development of this drug's renal tubule injury. L-carnitine, through its potential possible antioxidant effect, would have a nephro- protective effect against cisplatin-induced nephrotoxicity   aIssued also as CD 4aCisplatin 4aL-carnitine 4aNephrotoxicity0 aAhmed Abdelrahman Ahmed , eSupervisor0 aFatma Abdelhalim Mahmoud , eSupervisor0 aHanan Hosni Ahmed , eSupervisor  uhttp://172.23.153.220/th.pdf