TY - BOOK AU - Asmaa Mohammed Mahmoud Hussein AU - Ahmed Abdelrahman Ahmed , AU - Fatma Abdelhalim Mahmoud , AU - Hanan Hosni Ahmed , TI - Evaluation of the potential protective effect of L-carnitine on cisplatin induced nephrotoxicity in rats / PY - 2011/// CY - Cairo : PB - Asmaa Mohammed Mahmoud Hussein , KW - Cisplatin KW - L-carnitine KW - Nephrotoxicity N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pharmacology; Issued also as CD N2 - Nephrotoxicity has limited the clinical use of cisplatin in 25-30% of patients, even since the first dose. Although the exact mechanism of CP-induced nephrotoxicity is not well understood, several studies have suggested the involvement of oxidative stress in the development of this drug's renal tubule injury. L-carnitine, through its potential possible antioxidant effect, would have a nephro- protective effect against cisplatin-induced nephrotoxicity UR - http://172.23.153.220/th.pdf ER -